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Öğe Bilateral Breast Abscess Caused by E.coli in a Non-lactating Woman: A Rare Case(Aves, 2014) Simsek, Grcan; Gundes, Ebubekir; Tekin, Sakir; Tavli, SakirBreast abscess usually occurs during lactation and the responsible organism is often S. Aureus. Breast abscess in non-lactating women is extremely rare and limited data is available in the literature regarding this entity. In our study, a 36-year-old non-lactating female patient who developed bilateral breast abscess due to E. coli infection without any predisposing factors has been discussed in light of the literature.Öğe Effect of sex steroids on soleus muscle response in hypocalcemic medium (in vitro)(Academic Press Inc Elsevier Science, 2013) Kokcam, S. Said; Tekin, Sakir; Kartal, Adil; Ayaz, Murat; Sahin, Mustafa; Acar, Fahreddin; Cakir, MuratPurpose: Postoperative hypocalcemia is a frequently encountered complication of thyroid surgery. Since hypocalcemic symptoms are closely associated with sex, the aim of this study is to investigate the effects of sex steroids on muscle tissue under hypocalcemic conditions. Methods: Six groups consisting of control male (M), control female (F), gonadectomized male (M -), gonadectomized female (F-), estradiol- applied gonadectomized male (MX), and testosterone- applied gonadectomized female (FX) rats were used. Contraction recordings were obtained from soleus muscle flaps. Maximal tension (PT), frequency required for 50% of PT (F50), contraction velocity at F50 (V50), and changes in contraction values (d[PT], d[F50], d[V50]) between normocalcemic and hypocalcemic conditions were calculated. Results: d[PT], d[F50], and d[V50] were significantly higher in M - and MX groups compared with control M group. Whereas d[PT], d[F50], and d[V50] parameters of the F- group were significantly higher than control F group, d[F50] and d[PT] of the FX group showed no significant change and d[V50] for the FX group was significantly lower. A comparison of control groups showed that d[PT], d[F50], and d[V50] of the F group were significantly higher than those of the M group. Conclusion: Whereas absence of both testosterone and estradiol caused an increase in hypocalcemia- induced changes in contraction parameters of rat skeletal muscle, presence or application of testosterone clearly stabilized contraction parameters. (C) 2013 Elsevier Inc. All rights reserved.Öğe Our Primary Colorectal Lymphoma Experiences(Galenos Yayincilik, 2014) Gundes, Ebubekir; Cakir, Murat; Kucukkartallar, Tevfik; Tasci, Halil Ibrahim; Tekin, Ahmet; Tekin, SakirAim: In this paper, we aimed to present our surgical approach to ten patients who underwent surgery for primary colonic lymphoma and the features and clinical presentations of the tumors. Methods: We retrospectively analyzed the data of ten patients who underwent surgery in our clinic for primary colorectal lymphoma between January 2006 and December 2012. Results: The median age of the patients at the time of diagnosis was 66 (50-84) years. The most frequent presenting complaints were abdominal pain and change in bowel habits. The most frequent physical examination findings were abdominal distention and widespread tenderness. Three patients underwent emergency surgery subsequent to acute abdomen diagnosis. During the surgery, it was observed that one patient had ileocecal invagination, one patient had a mass that caused cecal perforation, and one other had an obstructive mass in the sigmoid colon. The most common localizations were the cecum (60%), sigmoid colon (30%), and the rectum (10%), respectively. The most frequent type was B- cell lymphoma (n=8). Conclusion: Primary colonic lymphoma is a rare condition. It is still yet uncertain whether surgery or chemotherapy should be advised first.Öğe Review of our ileal pouch experience in the light of literature(Turkish Surgical Assoc, 2015) Cakir, Murat; Dogan, Serhat; Kucukkartallar, Tevfik; Tekin, Ahmet; Tekin, SakirObjective: Retrospective proctocolectomy is a distinguished, sphincter saving treatment used for the treatment of ulcerative colitis and FAP disease. We aimed to evaluate ileal pouch interventions performed at our clinic and their results in the light of literature. Material and Methods: Medical records of 35 restorative proctocolectomy and J pouch ileo-anal anastomosis surgeries performed at Necmettin Erbakan University, Meram School of Medicine between the years 2006-2013 were retrospectively examined. The patients were assessed according to their age, gender, length of hospital stay, diagnosis, follow-up duration and pouch-related complications. All patients were contacted by phone and they were scheduled for controls at the outpatient clinic. Results: Nineteen patients were male (54%) and 16 were female (46%). Their mean age was 45 years (21-74). The mean length of hospital stay was 11 (5-20) days. Twenty two (63%) patients were operated on due to FAP, 12 (34%) due to synchronous rectum cancer and colon tumor or polyp, and one (3%) due to ulcerative colitis. All patients received J pouch and protective ileostomy. After the closure of ileostomy, two cases were identified to have J pouch fistulas. The patients were followed up for 6 months to 7 years. They were contacted by phone and they were questioned about their active complaints, number of defecations, urinary and sexual dysfunctions. It was identified that they had 5 (3-8) defecations per day on average and that 4 (11%) cases had one nocturnal defecation. No pouchitis were identified in the follow-up endoscopic examinations. Conclusion: Restorative proctocolectomy and ileo-anal anastomosis technique is a surgical procedure that can be performed with low rates of morbidity and mortality, including the elderly.