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Öğe Coexistence of Behcet's Disease and Ankylosing Spon-dylitis(Modestum Ltd, 2013) Kucuksen, Sami; Bagcaci, Sinan; Karahan, A. Yavuz; Sahin, Muhammed; Ugurlu, HaticeBehcet's disease (BD) is a disease which has effects on different systems. Genital ulcer, aphthous stomatitis and iritis are characterized by triple symptom complex of BD. BD is considered to be a systemic vasculitis. BD was previously accepted in spondy-loarthropathy (SSpA) group, but there are many reasons for not classifying BD as one of SSpA group. Ankylosing spondylitis (AS) is a prototype of seronegative spondyloarthropathy, and mainly axial skeleton is affected. In this paper, we aimed to present a-33-year old female patient with coexistence of BD and AS. In addition, the coexistence was aimed to be discussed.Öğe The effect of proprioception exercises on functional status in patients with anterior cruciate ligament reconstruction(Ios Press, 2015) Ordahan, Banu; Kucuksen, Sami; Tuncay, Ibrahim; Salli, Ali; Ugurlu, HaticeOBJECTIVE: To evaluate knee proprioception in patients with anterior cruciate ligament (ACL) injuries and to assess the effectiveness of an exercise program consisting mainly of proprioception exercises addressing pain, proprioception, and functional status following ACL reconstruction. MATERIALS AND METHODS: Twenty male patients, diagnosed with unilateral ACL injury and scheduled for reconstruction, participated in the study along with 16 age-and sex-matched healthy volunteers. Arthroscopic reconstruction of the ACL using autologous hamstring tendon was performed in every case by the same surgeon. After the operation, a six-month rehabilitation program was initiated. Knee proprioception, pain, and functional status were evaluated before and six months after the reconstruction. An isokinetic dynamometer was used to evaluate proprioception and a visual analog scale (VAS) and the Tegner Lysholm Knee Scoring Scale were used to evaluate pain and functional status respectively. RESULTS: Preoperative proprioception loss was detected on the patients' injured side when compared to the uninjured side and to healthy volunteers (p = 0.00). A significant improvement was found in pain severity, proprioception, and functional capacity after the postoperative six-month rehabilitation program (p = 0.00). CONCLUSION: Preoperative proprioception loss was detected in ACL-injured patients. The rehabilitation program predominantly consisting of proprioception exercises provided considerable improvement on knee proprioception and functional status.Öğe Efficacy of vitamin D replacement therapy on patients with chronic nonspecific widespread musculoskeletal pain with vitamin D deficiency(Wiley, 2016) Yilmaz, Ramazan; Salli, Ali; Cingoz, Havva Turac; Kucuksen, Sami; Ugurlu, HaticeAim: The objective of this study is the evaluation of the effect of vitamin D replacement treatment on musculoskeletal symptoms and quality of life in patients with chronic widespread musculoskeletal pain (CWP) including fibromyalgia (FM) and vitamin D deficiency. Method: Patients with nonspecific CWP and vitamin D deficiency (25-OH D3<25ng/mL) were included into the study. Replacement treatments of 50000IU/week oral vitamin D3 for 3months were given to the patients. Patients were assessed pre- and post-treatment in terms of serum levels of Ca, P, alkaline phosphatase, 25-OH D3, severity of pain (visual analogue scale [VAS]-pain), severity of asthenia (VAS-asthenia), Beck Depression Inventory (BDI), quality of life scale (Short Form [SF]-36), tender point count (TPC), severity of waking unrefreshed, headache, tenderness on tibia, meeting the criteria of FM, and level of patient satisfaction. Results: Fifty-eight patients with a mean age of 36.9 +/- 9.2years were included into the study. 25-OH D3 levels of patients elevated from 10.6 +/- 5.1ng/mL to 46.5 +/- 24.0ng/mL after replacement treatment (P<0.001). Marked decrease in VAS-pain, VAS-asthenia, severity of waking unrefreshed, TPC, and BDI and an evident increase in subgroups of SF-36 were established in patients after treatment (P<0.001). The number of FM+ patients was 30 (52%) before treatment and regressed to 20 (34%) after treatment (P=0.013); 85% of patients stated satisfaction with the treatment. Conclusions: Vitamin D replacement treatment in patients with nonspecific CWP has provided improvements in musculoskeletal symptoms, level of depression and quality of life of patients. Patients with CWP should be investigated for vitamin D deficiency.Öğe Evaluation of Sexual Dysfunction in Women with Rheumatoid Arthritis: A Controlled Study(Elsevier Sci Ltd, 2012) Yilmaz, Halim; Polat, Halime Almula Demir; Yilmaz, Sema Dereli; Erkin, Gulten; Kucuksen, Sami; Salli, Ali; Ugurlu, HaticeObjective. To evaluate sexual function in women with rheumatoid arthritis (RA) and compare them with healthy controls. Materials and Methods. Ninety-five patients with RA and 108 healthy controls were included in the study. Depression levels and sexual functions of all participants were evaluated by the Beck Depression Inventory (BDI) and Index of Female Sexual Function (IFSF), respectively. Morning stiffness in women with RA, pain (Visual Analog ScaleVAS), disability rate (Health Assessment QuestionnaireHAQ), and disease activity score (DAS-28) were defined. Results. Total IFSF and mean of IFSF subgroup scores and significance of sexual life score were lower in patients with RA than controls, whereas mean BDI score was higher. The mean of the total IFSF scores was significantly lower in patients with RA with BDI =17 than that of patients with BDI <17. The mean of the total IFSF score decreased as disease severity increased. There was a strong negative correlation between total IFSF and DAS-28 scores, a moderate negative correlation between total IFSF score and HAQ, BDI, VAS score, age, and morning stiffness, and weak negative correlation between total IFSF and body mass index. Conclusion. RA is observed to have negative effects on sexual functions of women. Presence of depressive symptoms with RA and increased disease severity increase the degree of sexual dysfunction. Women patients with RA should also be asked about their sexual lives while being evaluated. Yilmaz H, Polat HAD, Yilmaz SD, Erkin G, Kucuksen S, Salli A, and Ugurlu H. Evaluation of sexual dysfunction in women with rheumatoid arthritis: A controlled study. J Sex Med **;**:****.Öğe Full-length silicone insoles versus ultrasound-guided corticosteroid injection in the management of plantar fasciitis: A randomized clinical trial(Sage Publications Ltd, 2013) Yucel, Ufuk; Kucuksen, Sami; Cingoz, Havva T.; Anliacik, Emel; Ozbek, Orhan; Salli, Ali; Ugurlu, HaticeBackground: Plantar fasciitis often leads to disability. Optimal treatment for this clinical condition is still unknown. Objective: To compare the effectiveness of wearing a full-length silicone insole with ultrasound-guided corticosteroid injection in the management of plantar fasciitis. Study design: Randomized clinical trial. Methods: Forty-two patients with chronic unilateral plantar fasciitis were allocated randomly to have an ultrasound-guided corticosteroid injection or wear a full-length silicone insole. Data were collected before the procedure and 1 month after. The primary outcome measures included first-step heel pain via Visual Analogue Scale and Heel Tenderness Index. Other outcome measures were the Foot and Ankle Outcome Score and ultrasonographic thickness of the plantar fascia. Results: After 1 month, a significant improvement was shown in Visual Analogue Scale, Heel Tenderness Index, Foot and Ankle Outcome Score, and ultrasonographic thickness of plantar fascia in both groups. Visual Analogue Scale scores, Foot and Ankle Outcome Score pain, Foot and Ankle Outcome Score for activities of daily living, Foot and Ankle Outcome Score for sport and recreation function, and plantar fascia thickness were better in injection group than in insole group (p < 0.05). Conclusions: Although both ultrasound-guided corticosteroid injection and wearing a full-length silicone insole were effective in the conservative treatment of plantar fasciitis, we recommend the use of silicone insoles as a first line of treatment for persons with plantar fasciitis. Clinical relevance Silicone insole may be considered as a first-line treatment option in patients with plantar fasciitis.Öğe Muscle Energy Technique Versus Corticosteroid Injection for Management of Chronic Lateral Epicondylitis: Randomized Controlled Trial With 1-Year Follow-up(W B Saunders Co-Elsevier Inc, 2013) Kucuksen, Sami; Yilmaz, Halim; Salli, Ali; Ugurlu, HaticeObjective: To determine the short- and long-term effectiveness of the muscle energy technique (MET) compared with corticosteroid injections (CSIs) for chronic lateral epicondylitis (LE). Design: Randomized controlled trial with 1 year of follow-up. Setting: Outpatient clinic of a university's department of physical medicine and rehabilitation. Participants: Patients with chronic LE (N=82; 45 women, 37 men). Interventions: Eight sessions of MET, or a single CSI was applied. Main Outcome Measures: Grip strength, pain intensity, and functional status were assessed using the pain-free grip strength (PFGS), a visual analog scale (VAS), and the Disabilities of the Aim, Shoulder and Hand (DASH) questionnaire, respectively. Measurements were performed before beginning treatment and at 6, 26, and 52 weeks afterward. Results: When the baseline PFGS, VAS, and DASH scores were compared with the scores at the 52-week follow-up, statistically significant improvements were observed in both groups over time. The patients who received a CSI showed significantly better effects at 6 weeks according to the PFGS and VAS scores, but declined thereafter. At the 26- and 52-week follow-ups, the patients who received the MET were statistically significantly better in terms of grip strength and pain scores. At 52 weeks, the mean PFGS score in the MET group was significantly higher (75.08 +/- 26.19 vs 62.24 +/- 21.83; P=.007) and the mean VAS score was significantly lower (3.28 +/- 2.86 vs 4.95 +/- 2.36; P=.001) than those of the CSI group. Although improvements in the DASH scores were more pronounced in the MET group, the differences in DASH scores between the groups were not statistically significant. Conclusions: This study showed that while both MET and CSI improved measures of strength, pain, and function compared with baseline, subjects receiving MET had better scores at 52 weeks for PFGS and the VAS for pain. We conclude that MET appears to be an effective intervention in the treatment of LE. (C) 2013 by the American Congress of Rehabilitation MedicineÖğe Osteomalacia due to Vitamin D Deficiency: A Case Report(Galenos Yayincilik, 2020) Ordahan, Banu; Uslu, Kaan; Ugurlu, HaticeOsteomalacia is a metabolic bone disease characterized by demineralization of the newly formed osteoid in adults. Vitamin D deficiency due to insufficient vitamin D intake, inadequate exposure to sunlight, and malabsorption of vitamin D are the most widespread cause of osteomalacia. Here,we present the case of 18 year old female patient who presented to our hospital with complaints of low back pain. Sacral bone pseudofracture was detected by magnetic resonance imaging due to osteomalacia. Patient was treated with vitamin D.Öğe Pain in patients with multiple sclerosis(Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2023) Kasap, Zerrin; Ugurlu, HaticeObjectives: This study aims to identify the factors associated with pain and neuropathic pain (NP) in patients with multiple sclerosis (MS) and to determine the relationship between pain and NP with disability, functionality, activities of daily living, fatigue, mood, and quality of life (QoL).Patients and methods: Between July 2017 and October 2017, a total of 100 adult patients with MS (18 males, 82 females; mean age: 35.3 +/- 9.9 years; range, 19 to 71 years) were included. All patients were evaluated in terms of pain and NP. Patients with and without pain, and patients with and without NP were compared in terms of sociodemographic characteristics, disease data, disability, functionality, daily living activities, fatigue severity, mood, and QoL using various scales. Results: A total of 62% of the patients had pain. Pain was found to be associated with low education level (p=0.014), increased fatigue (p<0.001), depressive mood (p<0.001) and lower QoL (p<0.001). A total of 29.03% of patients with pain had NP. Patients with NP had a greater pain intensity (p<0.001) and fatigue (p=0.002) and lower QoL (p=0.011). The number of patients who received the correct treatment for their symptoms was low.Conclusion: Pain and NP should be better investigated and treated by physicians, as these symptoms are common in MS and adversely affect the QoL and social relations of affected patients and reduce their productivity.Öğe Quality of Life in Osteoporosis: A Controlled Study(Galenos Yayincilik, 2012) Yilmaz, Halim; Erkin, Gulten; Polat, Halime Almula Demir; Kucuksen, Sami; Salli, Ali; Ugurlu, HaticeAim: To evaluate quality of life in women without vertebral and nonvertebral fractures, with postmenopausal osteoporosis (PMO), osteopenic and normal bone mineral density (BMD), and to determine effective factors on quality of life. Materials and Methods: Without fractures, 266 women with PMO, 310 with osteopenia and 255 with normal women BMD were enrolled in the study. BMD measurement was performed on lumbar vertebra (L1-L4) and femur neck via dual energy X-ray absorbtiometry (DXA). Quality of life was assessed with Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO). QUALEFFO total scores and subscales were compared in all groups. Factors about quality of life in women with PMO were defined with correlation analysis. Variations of the highest correlation and quality of life were included into linear regression model. Results: In non-fractured women with PMO, QUALEFFO total scores and subscales were higher than those with osteopenia and normal BMD. In women with PMO, a positive correlation was found between QUALEFFO total scores, and age, Body Mass Index (BMI), parity and duration of menopause, and a negative correlation between QUALEFFO total scores, and level of education, economical status and femur neck BMD scores. In linear regression analysis, among significant factors of quality of life were BMI, femur neck BMD, parity and duration of menopause. Conclusion: Our results indicate that quality of life in non-fractured women with PMO is disordered higher than those with osteopenia and normal BMD, and quality of life are affected by numerous factors.
