Yazar "Varsak, Y. K." seçeneğine göre listele
Listeleniyor 1 - 3 / 3
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Animal models of acute otitis media - A review with practical implications for laboratory research(Elsevier Masson, Corporation Office, 2018) Davidoss, N. H.; Varsak, Y. K.; Maria, P. L. SantaConsiderable animal research has focused on developing new strategies for the prevention and treatment of acute otitis media (AOM). Several experimental models of AOM have thus been developed. A PubMed search of the English literature was conducted from 1975 to July 2016 using the search terms animal model and otitis media from which 91 published studies were included for analysis, yielding 123 animal models. The rat, mouse and chinchilla are the preferred animals for experimental AOM models with their individual advantages and disadvantages. The most common pathogens used to create AOM are Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis. Streptococcus pneumoniae (types 3, 23 and 6A) and non-typeable Haemophilus influenzae (NTHi) are best options for inoculation into rat and mouse models. Adding viral pathogens such as RSV and Influenza A virus, along with creating ET dysfunction, are useful adjuncts in animal models of AOM. Antibiotic prophylaxis may interfere with the inflammatory response without a significant reduction in animal mortality. (C) 2018 Elsevier Masson SAS. All rights reserved.Öğe Laryngeal fibrosarcoma: a case report(Galenos Yayincilik, 2012) Arbag, H.; Azgin, I.; Varsak, Y. K.; Yucel, H.Fibrosarcomas are the uncommon mesodermal origin tumors of the larynx. Radiation exposure are blamed in the etiology. Pathological examination and immunohistochemical staining plays an important role in diagnosis. Mainly treatment beside surgical treatment; adjuvant radiotherapy and chemotherapy is recommended causing high-grade tumors, positive surgical margins, large masses (>5 cm), and recurrent tumors. Twenty-three years-old male patient was seen in laryngeal fibrosarcoma; diagnosis and treatment options are discussed in this study because of its rarity.Öğe Nasopharyngeal dermoid cyst: case report(Galenos Yayincilik, 2012) Demir, H.; Yesildemir, H. S.; Varsak, Y. K.; Yucel, A.; Ozer, A. B.Dermoid tumors that take origin from ectoderm and mesoderm laminas, are a kind of teratoma and very rare tumors of the head and neck region. In general these lesions are stemmed, smooth surfaced, found on skin appendages and present with sympthoms ranging from intermittent cough and dysphagia to respiratory distress according to it's location and size. In our study we reported a nasopharyngeal dermoid cyst case in a 28-years-old male patient which is rarely encountered for nasopharynx and we also discussed the treatment methods along with literature.