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DOES PRIMARY TUMOR RESECTION AFFECT SURVIVAL IN ELDERLY PATIENTS WITH METASTATIC GASTRIC CANCER?
(Gunes Kitabevi Ltd Sti, 2016) Yalcin Musri, Fatma; Mutlu, Hasan; Karaagac, Mustafa; Gunduz, Seyda; Karakurt Eryilmaz, Melek; Kivrak Salim, Derya; Tazegul, Gokhan
Introduction: In this study, the effect of primary tumor resection (PTR) on the survival of patients with metastatic gastric carcinoma (mCG) aged over 65 years was aimed to be searched. Materials and Method: In total, 98 patients with mCG from the Akdeniz University, Necmettin Erbakan University, and Antalya Training and Research Hospital databases who were aged over 65 years were retrospectively evaluated. The patients were divided into two groups based on PTR: PTR (+) and PTR (-). Results: The median progression-free survival in the PTR (+) group was 10.2 months (95% confidence interval [CI] 6.6-13.7) and in the PTR (-) group was 5.9 months (95% CI 2.6-9.3) (p=0.054). When we evaluated the overall survival (OS) of the groups, the median OS was significantly higher in the PTR (+) group (11.5 months, 95% CI 8.4-14.6) than in the PTR (-) group (7.2 months, 95% CI 4.3-10.0) (p=0.001). In the final multivariate analysis, none of the parameters studied were independent prognostic factors. Conclusion: PTR may be beneficial for the survival of patients with mGC aged over 65 years.