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Öğe An Analysis of Disorders Presenting at a Pediatric Neurology Outpatient Clinic: A Report from Turkey(Georg Thieme Verlag Kg, 2022) Sarikaya, Emre; Yavuz, HalukY Neurological problems constitute an important part of diseases in children. Studies evaluating neurological diseases in children collectively and reporting their types and rates are very few. We report the clinical and laboratory spectra of children presenting with neurological diseases to our clinic. The charts of patients who presented for the first time to the only pediatric neurology outpatient clinic in the region during a year were evaluated retrospectively. A total of 88,785 patients were seen at the Meram Faculty of Medicine pediatric outpatient clinics in 1 year; 5.5% (4,904) of these patients were seen at the child neurology clinic and 1,807 patients (36.8%) were seen for the initial evaluation. Medical charts of 1,685 (93.2%) patients were reviewed: 952 (56.5%) were male patients and 733 were females. The mean age was 5.77 +/- 4.92 years; 30.9% of the patients had a similar disease in the family. The top three presenting complaints that led to hospital seen were seizures (12.2%), paroxysmal events (10%), and headaches (9.2%). The most common diagnoses were epilepsy (18%), headache (8.6%), and developmental delay (7.8%). Our study describes the characteristics of the large number of patients seen for the first time in the child neurology outpatient clinic.Öğe Homozygous LNPK gene mutation in neurodevelopmental disorder: case report(Academic Press Inc Elsevier Science, 2021) Duymus, Fahrettin; Tulgar, Busra Goksel; Esin, Deniz; Cora, Tulun; Yavuz, Haluk[Abstract Not Availabe]Öğe Toxic epidermal necrolysis treated with N-acetylcysteine(Wiley-Blackwell, 2014) Yavuz, Haluk; Emiroglu, MelikeAdverse drug reactions are the major cause of morbidity and mortality worldwide. Cutaneous drug reaction is the most common type of adverse reaction. Toxic epidermal necrolysis (TEN) is a rare, life-threatening mucocutaneous disease, usually attributable to drugs. There is no proven therapy for TEN. The mainstay of therapy is immediate withdrawal of the culprit drug, using disease-modifying agents, and meticulous supportive care. Several disease-modifying agents have been used such as steroid, i.v. human immunoglobulin (IVIg), plasmapheresis. A 10-year-old epileptic girl was admitted with lamotrigine-induced TEN. She was unresponsive to steroid. Her condition deteriorated despite IVIg treatment. She was treated with N-acetylcysteine (NAC). To our knowledge this is the first report of a child with TEN, a potentially lethal disorder, treated with NAC. NAC may be effective for children with TEN.Öğe West syndrome and pschycomotor retardation(Aves, 2013) Yavuz, Haluk; Ayyildiz, Vesile Betul[Abstract Not Availabe]
