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Öğe DETERMINATION OF RELIABILITY OF SOME TESTS IN EVALUATING AV FISTUL FLOW RATE IN HEMODIALYSIS PATIENTS(Oxford Univ Press, 2013) Yavuz, Yasemin Coskun; Selcuk, Nedim Yilmaz; Guney, Ibrahim; Altintepe, Lutfullah[Abstract Not Availabe]Öğe The Efficacy of Cinacalcet in the Treatment of Hyperparathyroidism in Turkish Hemodialysis Patient Population(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2016) Altunoren, Orcun; Gungor, Ozkan; Eren, Necmi; Tanrisev, Mehmet; Hur, Ender; Turkmen, Kultigin; Yavuz, Yasemin CoskunOBJECTIVE: Cinacalcet reduces parathyroid hormone levels by increasing the sensitivity of the parathyroid gland to calcium. In this study, we firstly aimed to evaluate the efficacy of cinacalcet in Turkish hemodialysis patients. MATERIAL and METHODS: 4483 hemodialysis patients were screened and 469 patients who had used cinacalcet were included in the study. The patients were divided into 4 groups according to drug usage durations (Group 1: 3 months, Group 2: 6 months, Group 3: 9 months and Group 4: 12 months). The patients' Parathormone, Ca, P and CaxP levels at the 3rd, 6th, 9th and 12th months were compared to the start of treatment and previous months. RESULTS: The levels of Parathormone, Ca, P and CaxP significantly decreased compared to their initial levels in all groups (from 1412 pg/ml to 1222 pg/mL for Parathormone, p< 0,001) in the 3rd month. However, this reduction was not continued in the subsequent months (Parathormone: 1381 pg/ml for the 12th month). CONCLUSION: Cinacalcet may not provide adequate benefit in control of hyperparathyroidism in Turkish hemodialysis patient population.Öğe Irritable bowel syndrome frequency and related factors in hemodialysis patients(Wiley, 2020) Ozkul, Durmus; Guney, Ibrahim; Sackan, Fatih; Yavuz, Yasemin Coskun; Yilmaz, Nedim; Tonbul, Halil Z.Introduction Irritable bowel syndrome (IBS) is a functional bowel disease that is common in society, does not threaten life, impairs quality of life, and causes serious economic losses. Gastrointestinal system complaints and especially IBS are common in patients with chronic kidney disease. It has also been shown that psychiatric diseases are more common in patients with IBS. In this study, we aimed to determine the frequency of IBS in hemodialysis patients and to investigate the factors associated with IBS. Methods In this cross-sectional study, the questionnaire prepared to evaluate depression, anxiety, and abdominal pain was administered face-to-face to 686 patients by the same researcher in seven dialysis centers; 404 patients without exclusion criteria were included in the study. The diagnosis of IBS was made according to Rome IV criteria. A multivariate logistic regression model was used to identify factors that are significantly related to IBS. Findings In 69 (17.1%) of the patients included in the study, symptoms were consistent with IBS. Binominal logistic regression analysis was performed to evaluate the effect of age, dialysis duration, diabetes, proton pump inhibitor, non-steroidal anti-inflammatory drugs, calcium acetate use, Hamilton depression and anxiety scores associated with IBS in the presence of IBS of the participants. The logistic regression model was statistically significant, chi(2) (3) = 69.748, P < 0.001. Independent risk factors for IBS in hemodialysis patients were determined as anxiety, long-term dialysis treatment, and using calcium acetate as a phosphorus binder. Discussion In hemodialysis patients, IBS occurs approximately twice as often as in a healthy population. Independent risk factors for IBS in hemodialysis patients are anxiety, long-term dialysis treatment, and using calcium acetate as a phosphorus binder.Öğe SARC-F is a Weaker Predictor Compared to Muscle Strength and a Stronger Predictor Compared to Muscle Mass for Mortality and Hospitalization in Hemodialysis Patients(Aves, 2022) Yavuz, Yasemin Coskun; Biyik, Zeynep; Korez, Muslu Kazim; Abusoglu, Sedat; Ahmadli, Nicat; Eryavuz, Duygu; Batur, ElifObjective: It is known that muscle strength and muscle mass decrease in hemodialysis patients. We aimed to compare the effect of SARC-F (strength, assistance with walking, rising from a chair, climbing stairs, and falls) questionnaire with that of handgrip strength and skeletal muscle mass/body mass index on 1-year mortality and hospitalization in hemodialysis patients. Methods: SARC-F test was filled for 67 hemodialysis patients, muscle strength was evaluated with handgrip strength, muscle mass was evaluated by performing bioimpedance analysis, and skeletal muscle mass/body mass index was evaluated by using the formula. Results: The end of 1 year revealed that 12 of 67 patients (17.9%) died. Of the patients, 38 (56.7%) were hospitalized. The number of hospitalizations was in the range of 0-9. The length of hospitalization varied between 2 and 77 days. The patients with low handgrip strength had a 9.86 times higher mortality risk (odds ratio = 9.862, 95% CI = 1.190-81.707, P =.034) and had a 5.27 times higher risk of hospitalization (odds ratio = 5.273, 95% CI = 1.828-15.207, P =.002). The patients who had lower SARC-F had a 3.88 times higher risk of hospitalization (odds ratio = 3.882, 95% CI = 1.340-11.252, P =.012). A positive statistically significant correlation was found between the patients' hospitalization periods and SARC-F scores (Spearman's rho = 0.329, P =.007), and a negative statistically significant correlation was found between the patients' hospitalization periods and handgrip strength scores. The duration of hospitalization was found to be significantly longer in the patients who had low handgrip strength (19.38 +/- 22.25). Conclusion: SARC-F appears to be a weaker parameter than handgrip strength and a stronger parameter than skeletal muscle mass/body mass index on hospitalization and mortality.
