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  • Küçük Resim Yok
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    Effect of Pericardial Effusion on Right Ventricular Functions in Oncology Patients Receiving Chemotherapy
    (Galenos Publ House, 2023) Tatar, Sefa; Yavuz, Yunus Emre; Oktay, Irem; Aydin, Nergiz; Alsancak, Yakup; Icli, Abdullah
    Introduction: Pericardial effusion is an indicator of poor prognosis in patients with cancer. We investigated the effect of pericardial effusion development on right ventricular function in oncology patients receiving chemotherapy for malignancy. Methods: A total of 90 patients who were followed up in the oncology clinic and who applied to our outpatient clinic for routine cardiac examination were included in the study. Echocardiography was performed on the patients, and they were divided into two groups: patients with and without pericardial effusion. Demographic characteristics and, clinical and laboratory findings of the patients were recorded. The right ventricular functions of the patients were then evaluated. Results: Pericardial effusion was in 30 (33.3%) of 90 patients included in the study. The mean age of patients without pericardial effusion was 57.33 +/- 15.59, and the mean age of patients with effusion was 60.27 +/- 13.51, and it was similar between the groups (p=0.36). No statistically significant difference was detected between the groups in right ventricular (RV) fractionated area change, RV-early peak, tricuspid annular plane systolic excursion, pulmonary artery pressure, E/E', and heart failure with preserved ejection fraction values, which are parameters that indicate right ventricular functions and diastolic dysfunction. However, RV systolic velocity and RV-AM, which are indicators of diastolic dysfunction, were found at higher rates in the patient group with pericardial effusion (p-value 0.041 and 0.001, respectively). In addition, Mitral E velocity was found to be lower in the patient group with pericardial effusion (p=0.032). Conclusion: In malignancy patients who develop pericardial effusion, we recommend that diastolic parameters be checked and close clinical follow-up of the patients be performed before overt heart failure clinic develops. It should be kept in mind that the development of pericardial effusion in oncology patients receiving chemotherapy does not mean right ventricular failure.
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    Korunmuş ejeksiyon fraksiyonlu kalp yetmezliği hastalarında sistemik ve pulmoner arteriyel sertlik parametrelerinin, HFPEF skorları (H2FPEF, HFA-PEFF) ve diyastolik disfonksiyon parametreleriyle olan ilişkisi
    (Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, 2021) Yavuz, Yunus Emre; Soylu, Ahmet
    Amaç: Bu çalışmadaki amacımız HFpEF hastalarının rutin kontrolleri esnasında non-invaziv şekilde ekokardiyografik olarak ölçülebilen pulmoner pulse wave transit time (pPTT), pulmoner arteryel sertlik (PAS) ve tansiyon holter cihazıyla bakılabilen aortik sertliğe yönelik parametrelerin; HFpEF skorlamaları (H2FPEF, HFA-PEFF), bu skorlamalar kılavuzluğunda tanı konan HFpEF hastaları ve diyastolik disfonksiyon ile olan ilişkisini ortaya koymaktır. Yöntem: Çalışmamıza merkezimiz kardiyoloji kliniğinde takipli klinik, laboratuvar ve ekokardiyografik olarak tanı konmuş 52 HFpEF hastası ve Kardiyoloji polikliniğine muayene olup kalp yetmezliği olmayan 49 adet kontrol grubu hasta olmak üzere toplam 101 vaka alındı. Ekokardiyografi ile değerlendirme konvansiyonel ekokardiyografi, doku doppler görüntüleme, strain görüntüleme yöntemleriyle yapıldı. HFpEF tanısını destekleyen diyastolik parametreler ve pulmoner arteryel sertliğe yönelik ekokardiyografik parametreler hesaplandı. Aort sertliğine yönelik değerlendirme PWA monitörle yapıldı. Hastaların demografik özellikleri, laboratuar bulguları, pulmoner arteryel parametreleri de içeren ekokardiyografi bulguları ve aort sertliğine yönelik sonuçları kontrol grubuyla karşılaştırıldı. Bulgular: Yaş, cinsiyet, diyabet, hipertansiyon, hiperlipidemi, koroner arter hastalığı ve sigara öyküsünü içeren temel özellikler HFpEF ve kontrol grubu arasında benzerdi. PAS, HFpEF grubunda kontrol grubuna kıyasla daha yüksek (18.4(15.7-21.8) / 14.2(13-16.3),
  • Küçük Resim Yok
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    The relationship of systemic and pulmonary arterial parameters with HFpEF scores (H2FPEF, HFA-PEFF) and diastolic dysfunction parameters in heart failure patients with preserved ejection fraction
    (Wiley, 2024) Yavuz, Yunus Emre; Soylu, Ahmet; Gurbuz, Ahmet Seyfettin
    Objective: We aimed to show the relationship between pulmonary pulse wave transit time (pPTT), pulmonary artery stiffness (PAS), and aortic stiffness parameters measured by non-invasive methods, HFpEF patients, and HFpEF scores (H2FPEF, HFA-PEFF).Method: A total of 101 patients were included in our study, 52 of whom were HFpEF patients and 49 were control groups without heart failure. Echocardiographic parameters for PAS and pPTT were calculated, along with diastolic parameters that support the diagnosis of HFpEF. Aortic stiffness was assessed using a PWA monitor. Demographic features, laboratory findings, aortic stiffness parameters, and echocardiographic findings including pulmonary artery parameters were compared with the control group.Results: PAS, pPTT, PWV were significantly higher in the HFpEF group than in the control group (p < 0.001). PAS and pPTT correlated positively with HFpEF scores. In linear regression analysis for PAS, a directly positive correlation was found between E/e' and PAS, independent of aortic stiffness.Conclusion: These parameters can be used as a predictive value in the diagnosis process of patients with suspected HFpEF. A significant relationship between PAS and ventricular stiffness (E/e') was shown independently of aortic stiffness.