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Öğe Benefits of the Neutrophil-to-Lymphocyte Ratio for the Prediction of Gestational Diabetes Mellitus in Pregnant Women(Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh, 2014) Yilmaz, H.; Celik, H. T.; Namuslu, M.; Inan, O.; Onaran, Y.; Karakurt, F.; Ayyildiz, A.Aims: There is growing consensus in the literature that inflammation plays a central role in the pathophysiology of obesity, Type 2 Diabetes Mellitus (T2DM), Gestational Diabetes Mellitus (GDM) and cardiovascular complications. Measuring the neutrophil-to-lymphocyte ratio (NLR) provides a simple inexpensive method for the assessment of inflammatory status. We investigated the predictive value of pre-procedural (before the oral glucose tolerance test (OGTT)) NLR on the development of GDM in pregnancy. Methods: 42 women with GDM and 68 women without GDM were included in the study. Complete Blood Count and biochemical tests were followed by a diagnostic 4-point 100-g-OGTT within 2 weeks. GDM was diagnosed by the Carpenter and Coustan criteria. The NLR was calculated from the data. Results: The mean NLR level was significantly higher in GDM women (3.00 +/- 0.83 vs. 2.26 +/- 0.43 p < 0.001, respectively). In ROC analysis, NLR > 2.93 had 76.2 % sensitivity and 94.1 % specificity in predicting GDM. Logistic regression analysis showed that elevated NLR (OR: 5.512, 95 % CI: 1.352-22.475, p = 0.017) was an independent variable for predicting GDM in pregnancy. Conclusions: An elevated NLR level is a powerful and independent predictor of GDM. The results of this study suggested that inflammation plays a central role in the pathogenesis of GDM.Öğe Candida albicans infection of cervix and comparison of Pap smear and culture in diagnosis(Imr Press, 2020) Cengiz, T.; Ozer, T. Toka; Kilinc, F.; Selimoglu, R.; Yilmaz, H.Purpose: The Pap smear is a routine screening test for the detection of cervical abnormalities viral, bacterial, and fungal infections of the uterine cervix, The aim of this study is to investigate if Pap smear is an alternative to cervicovaginal culture in the diagnosis of asymptomatic Candida. Materials and Methods: A retrospective analysis of 133 non-pregnant asymptomatic cases were included. Candida spp. positive cases in Pap smear and/or culture were compared. Results: Candida spp. was found in 45 cases in culture and 40 cases of Candida in Pap smear examination. The sensitivity of Pap smear was 88%, specificity was 100%, the positive predictive value was 100%, the negative predictive value was 94%, and the overall power of the test (test validity) was 96%. It was detected that 33.83% of the asymptomatic cases had Candida infection. Conclusion: Pap smear can be used as a first-line examination method.Öğe The effect of obesity surgery on ghrelin levels(Wiley, 2017) Ayranci, M.; Vatansev, H.; Saracligil, B.; Tekin, G.; Yilmaz, H.; Vatansev, H.[Abstract Not Availabe]Öğe Invasive fungal diseases in patients with acute leukemia or allogeneic stem cell transplantion recepients: A prospective multicenter observational study(Oxford Univ Press, 2018) Metan, G.; Etgul, S.; Cifticioglu, A.; Saba, R.; Kilic, A. Ulu; Yilmaz, H.; Demir, K.[Abstract Not Availabe]Öğe Posaconazole prophylaxis in patients with acute myeloid leukemia: A real life experience from a prospective multicenter observational study(Oxford Univ Press, 2018) Metan, G.; Etgul, S.; Cifticioglu, A.; Saba, R.; Kilic, A. Ulu; Yilmaz, H.; Demir, K.[Abstract Not Availabe]
