Bing-Neel syndrome: A case reports

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dc.contributor.authorDemircioglu, Sinan
dc.contributor.authorOltulu, Pembe
dc.contributor.authorEmlik, Ganime D.
dc.contributor.authorTekinalp, Atakan
dc.contributor.authorCeneli, Ozcan
dc.date.accessioned2024-02-23T14:27:01Z
dc.date.available2024-02-23T14:27:01Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractIntroduction Bing-Neel syndrome (BNS) is a rare complication of of Waldenstrom macroglobulinemia (WM) identified by involvement of central nervous system (CNS) lymphoplasmacytic cells. Case report We present a patient who was diagnosed with Bing-Neel syndrome four years after the diagnosis of Waldenstrom macroglobulinemia. Management & outcome The patient was admitted with neurological symptoms. There were lesions associated with WM involvement on brain imaging. The diagnosis was made by brain biopsy. High dose methotrexate treatment was given. Discussion CNS infiltrating agents such as fludarabine, methotrexate and cytarabine are often used in BNS treatment. Ibrutinib, which is a new bruton tyrosine kinase inhibitor, has recently started to be used in BNS treatment, as it has been shown to be effective and penetrate the CNS.en_US
dc.identifier.doi10.1177/1078155220983426
dc.identifier.endpage1761en_US
dc.identifier.issn1078-1552
dc.identifier.issn1477-092X
dc.identifier.issue7en_US
dc.identifier.pmid33356992en_US
dc.identifier.scopus2-s2.0-85098212499en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1758en_US
dc.identifier.urihttps://doi.org/10.1177/1078155220983426
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14425
dc.identifier.volume27en_US
dc.identifier.wosWOS:000626684900001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal Of Oncology Pharmacy Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectWaldenströ M Macroglobulinemiaen_US
dc.subjectBing-Neel Syndromeen_US
dc.subjectIbrutiniben_US
dc.titleBing-Neel syndrome: A case reportsen_US
dc.typeArticleen_US

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