Dynamic changes in aortic stiffness after substantial weight loss by laparoscopic sleeve gastrectomy in patients with obesity: a 1-year follow-up study

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dc.contributor.authorGul, Murat
dc.contributor.authorInci, Sinan
dc.contributor.authorAktas, Halil
dc.contributor.authorYildirim, Oguz
dc.contributor.authorAlsancak, Yakup
dc.contributor.authorOzkan, Namik
dc.date.accessioned2024-02-23T14:26:13Z
dc.date.available2024-02-23T14:26:13Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractArterial stiffness has been identified as a powerful and independent risk factor for cardiovascular disease. Obesity is associated with an increased risk of aortic stiffness (AS) and adverse cardiovascular events. Herein, we aimed to evaluate the effects of weight loss after laparoscopic sleeve gastrectomy (LSG) on AS in individuals with morbid obesity by using the transthoracic echocardiography (TTE). A total of 53 patients with obesity (17 males, 36 females) who underwent LSG and did not have any known heart disease were included in the study. The AS parameters were measured with TTE. The demographic and echocardiographic data of the patients were studied before, at 1 month and 12 months after surgery. The mean age of the study group was 34.41 +/- 11.62, 68% of whom were female. There were no significant differences in terms of the standard echocardiography and Doppler measurements as compared with preoperative values (all p>0.05). When the elastic parameters of the aorta were compared, no significant differences were detected regarding aortic strain (%) ((16.28 +/- 4.11) vs (16.68 +/- 4.56), p=(0.998)), distensibility (cm(2)/dyn) ((6.74 +/- 1.78) vs (7.03 +/- 2.31), p=(0.997)) and Aortic Stiffness Index values ((10.73 +/- 3.84) vs (10.63 +/- 3.34), p=0.998) between baseline and first month after surgery. In the 12-month follow-up, it was determined that the aortic strain ((16.28 +/- 4.11) vs (22.74 +/- 5.79), p <= 0.001) and distensibility ((6.74 +/- 1.78) vs (10.34 +/- 3.059), p<0.001)) values increased at significant levels. Weight loss by LSG improves arterial stiffness parameters in patients with obesity over a 1-year follow-up.en_US
dc.identifier.doi10.1136/jim-2021-001778
dc.identifier.endpage1174en_US
dc.identifier.issn1081-5589
dc.identifier.issn1708-8267
dc.identifier.issue6en_US
dc.identifier.pmid33771842en_US
dc.identifier.scopus2-s2.0-85103462526en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1168en_US
dc.identifier.urihttps://doi.org/10.1136/jim-2021-001778
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14110
dc.identifier.volume69en_US
dc.identifier.wosWOS:000680407000006en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal Of Investigative Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectVascular Stiffnessen_US
dc.subjectGastrectomyen_US
dc.subjectObesityen_US
dc.titleDynamic changes in aortic stiffness after substantial weight loss by laparoscopic sleeve gastrectomy in patients with obesity: a 1-year follow-up studyen_US
dc.typeArticleen_US

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