Rapid green synthesis of non-cytotoxic silver nanoparticles using aqueous extracts of 'Golden Delicious' apple pulp and cumin seeds with antibacterial and antioxidant activity

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dc.contributor.authorJahan, Israt
dc.contributor.authorErci, Fatih
dc.contributor.authorIsildak, Ibrahim
dc.date.accessioned2024-02-23T14:00:13Z
dc.date.available2024-02-23T14:00:13Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractA simple, facile and rapid microwave irradiated system was applied to synthesize silver nanoparticles using 'Golden Delicious' apple pulp (Malus domestica) and cumin (Cuminum cyminum) seed extracts. The phytosynthesized AgNPs were characterized by Ultraviolet-Visible Spectroscopy (UV-vis), Fourier transform infrared (FTIR), X-ray Diffraction (XRD) Transmission Electron Microscopy (TEM) and Zeta sizer analysis. In the study, the presence of face-centered cubic crystalline structured metallic silver in AgNPs from apple and cumin extracts and the monodisperse nature of AgNPs with the size distribution range of 5.46-20 nm and 1.84-20.57 nm were confirmed, respectively. This study established an efficient green synthesis approach that created so far, the smallest silver nanoparticles by using these two extracts. According to the results obtained, AgNPs synthesized using both extracts were non-toxic against L929 mouse fibroblast cells, while they were effective against both Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria with a greater effect on S. aureus. Moreover, AgNPs synthesized through cumin extract exhibited a higher ABTS scavenging ability (96.43 +/- 0.78% at 160 mu g/mL) in comparison to apple pulp extract mediated AgNPs, while both AgNPs showed lower activity for DPPH (27.84 +/- 0.56% and 13.12 +/- 0.32% from cumin seed and apple pulp extracts, respectively). In summary, our results suggest the green non-cytotoxic AgNPs synthesized in this study could be a promising template for further biological and clinical applications. [GRAPHICS]en_US
dc.identifier.doi10.1007/s42452-020-04046-6
dc.identifier.issn2523-3963
dc.identifier.issn2523-3971
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85100653380en_US
dc.identifier.urihttps://doi.org/10.1007/s42452-020-04046-6
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11515
dc.identifier.volume3en_US
dc.identifier.wosWOS:000608199900030en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer Int Publ Agen_US
dc.relation.ispartofSn Applied Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMalus Domesticaen_US
dc.subjectCuminum Cyminumen_US
dc.subjectMicrowave-Irradiated Synthesisen_US
dc.subjectSilver Nanoparticlesen_US
dc.subjectNon-Cytotoxicen_US
dc.titleRapid green synthesis of non-cytotoxic silver nanoparticles using aqueous extracts of 'Golden Delicious' apple pulp and cumin seeds with antibacterial and antioxidant activityen_US
dc.typeArticleen_US

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