Vitamin D Deficiency Is a Potential Risk for Blood Pressure Elevation and the Development of Hypertension

Basit Öğe Kaydı
dc.contributor.authorKaradeniz, Yusuf
dc.contributor.authorOzpamuk-Karadeniz, Fatma
dc.contributor.authorAhbab, Sueleyman
dc.contributor.authorAtaoglu, Esra
dc.contributor.authorCan, Guenay
dc.date.accessioned2024-02-23T14:35:14Z
dc.date.available2024-02-23T14:35:14Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractBackground and objectives: Hypertension is a global health problem and a major risk factor for cardiovascular diseases. Vitamin D deficiency is closely related to high blood pressure and the development of hypertension. This study investigated the relationship between the vitamin D and blood pressure status in healthy adults, and their 8-year follow-up was added. Materials and Methods: A total of 491 healthy middle-aged participants without any chronic illness, ages 21 to 67 at baseline, were divided into two groups as non-optimal blood pressure (NOBP) and optimal blood pressure (OBP). NOBP group was divided into two subgroups: normal (NBP) and high normal blood pressure (HNBP). Serum 25-hydroxy vitamin D levels were measured with the immunoassay method. 8-year follow-up of the participants was added. Results: The average vitamin D level was detected 32.53 +/- 31.50 nmol/L in the OBP group and 24.41 +/- 14.40 nmol/L in the NOBP group, and a statistically significant difference was found (p < 0.001). In the subgroup analysis, the mean vitamin D level was detected as 24.69 +/- 13.74 and 24.28 +/- 14.74 nmol/L in NBP and HNBP, respectively. Together with parathyroid hormone, other metabolic parameters were found to be significantly higher in the NOBP. During a median follow-up of 8 years, higher hypertension development rates were seen in NOBP group (p < 0.001). Conclusions: The low levels of vitamin D were significantly associated with NBP and HNBP. The low levels of vitamin D were also associated with the development of hypertension in an 8-year follow-up.en_US
dc.identifier.doi10.3390/medicina57121297
dc.identifier.issn1010-660X
dc.identifier.issn1648-9144
dc.identifier.issue12en_US
dc.identifier.pmid34946242en_US
dc.identifier.scopus2-s2.0-85121146803en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.3390/medicina57121297
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15943
dc.identifier.volume57en_US
dc.identifier.wosWOS:000735489300001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofMedicina-Lithuaniaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectVitamin Den_US
dc.subjectBlood Pressureen_US
dc.subjectHypertensionen_US
dc.subjectParathyroid Hormoneen_US
dc.titleVitamin D Deficiency Is a Potential Risk for Blood Pressure Elevation and the Development of Hypertensionen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu