Lathyrus aureus and Lathyrus pratensis: characterization of phytochemical profiles by liquid chromatography-mass spectrometry, and evaluation of their enzyme inhibitory and antioxidant activities

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dc.contributor.authorLlorent-Martinez, E. J.
dc.contributor.authorOrtega-Barrales, P.
dc.contributor.authorZengin, G.
dc.contributor.authorUysal, S.
dc.contributor.authorCeylan, R.
dc.contributor.authorGuler, G. O.
dc.contributor.authorMocan, A.
dc.date.accessioned2024-02-23T14:16:46Z
dc.date.available2024-02-23T14:16:46Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractDifferent wild plants commonly used in folk medicine, such as different species from the genus Lathyrus, may represent new sources of biologically active compounds. Hence, a study of the composition and (bio)chemical behaviour of extracts from these plants may provide valuable information. To evaluate the phytochemical profile, and the enzyme inhibition and antioxidant activities of the aerial parts of L. pratensis and L. aureus, extracts from both plants were analyzed by high-performance liquid chromatography with electrospray ionization mass spectrometric detection (HPLC-ESI-MSn). The in vitro antioxidant activity (phosphomolybdenum, beta-carotene bleaching, DPPH, ABTS, FRAP, CUPRAC and metal chelating) and enzyme inhibitory activity (acetyl cholinesterase, butyrylcholinesterase, tyrosinase, alpha-amylase and alpha-glucosidase) were also investigated for these Lathyrus species. Flavonoids and saponins were the main groups of compounds detected in the extracts from both plants. Generally, the methanol and water extracts presented remarkable antioxidant and enzyme inhibitory effects; all the observed results are critically discussed. The content of organic compounds and the antioxidant and enzyme assays suggest that these plants may be further used in phytopharmaceutical or food industry applications.en_US
dc.description.sponsorshipUCLM Research Plan; Scientific and Technological Research Council of Turkey (TUBITAK) [113Z892]en_US
dc.description.sponsorshipE. J. Llorent-Martinez acknowledges the financial support from the UCLM Research Plan. CICT from University of Jaen is also acknowledged. This research was also supported by The Scientific and Technological Research Council of Turkey (TUBITAK) (Project Number: 113Z892).en_US
dc.identifier.doi10.1039/c6ra17170b
dc.identifier.endpage89006en_US
dc.identifier.issn2046-2069
dc.identifier.issue92en_US
dc.identifier.scopus2-s2.0-84988553105en_US
dc.identifier.startpage88996en_US
dc.identifier.urihttps://doi.org/10.1039/c6ra17170b
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12787
dc.identifier.volume6en_US
dc.identifier.wosWOS:000384441200011en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherRoyal Soc Chemistryen_US
dc.relation.ispartofRsc Advancesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titleLathyrus aureus and Lathyrus pratensis: characterization of phytochemical profiles by liquid chromatography-mass spectrometry, and evaluation of their enzyme inhibitory and antioxidant activitiesen_US
dc.typeArticleen_US

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