The effect of acute kidney injury on the success of non-invasive ventilation in COPD patients with hypercapnic respiratory failure

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dc.contributor.authorInce, Mahmut Sami
dc.contributor.authorTeke, Turgut
dc.contributor.authorKaragoz, Ali
dc.contributor.authorYucel, Fatih
dc.contributor.authorDemirbas, Soner
dc.contributor.authorKorkmaz, Celalettin
dc.date.accessioned2024-02-23T14:49:17Z
dc.date.available2024-02-23T14:49:17Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractObjective: To investigate the effect of acute kidney injury (AKI) on the success of noninvasive ventilation in chronic obstructive pulmonary disease (COPD) patients with hypercapnic respiratory failure Design: Retrospective observational cohort study Setting: Faculty of Meram Medicine, Necmettin Erbakan University, Konya, Turkey Subjects: This clinical study included 55 patients with decompensated COPD: 29 patients with AKI and 26 patients without AKI. Intervention: Demographical data, APACHE II scores, urea and creatinine values before non-invasive mechanical ventilation (NIMV) administration were recorded. Main outcome measures: The effect of AKI on the success of NIMV Results: There was no significant difference between sex, age and baseline respiratory rate of groups. There were statistically significant differences in baseline mean APACHE II score (21.4 +/- 5.3 vs 18.3 +/- 4.6, p=0.028), baseline mean pH (7.23 +/- 0.1 vs 7.30 +/- 0.1, p=0.001), urea (113.7 +/- 43.6 vs 45.2 +/- 13.0, p<0.001) and creatinine values (3.1 +/- 2.0 vs 0.9 +/- 0.3, p<0.001) of Group 1 and Group 2. Logistic regression analysis showed that none of these variable values tested have any effect on NIMV outcomes. Of the baseline variables tested, age (OR: 0.85; 95% CI: 0.69 to 1.07), sex (OR: 1.29; 95% CI: 0.89 to 1.89), baseline respiratory rate (OR: 1.02; 95% CI: 0.92 to 1.14), APACHE II score (OR: 1.03; 95% CI: 0.87 to 1.23), and AKI (OR: 0.79; 95% CI: 0.15 to 4.18) were not related to the outcome of NIMV in the logistic regression. Conclusions: We determined that AKI did not affect the outcome of NIMV in decompensated COPD patients.en_US
dc.identifier.endpage54en_US
dc.identifier.issn0023-5776
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85089716117en_US
dc.identifier.startpage50en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12452/18103
dc.identifier.volume52en_US
dc.identifier.wosWOS:000540762200009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherKuwait Medical Assocen_US
dc.relation.ispartofKuwait Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute Kidney Injuryen_US
dc.subjectCopden_US
dc.subjectHypercapnic Respiratory Failureen_US
dc.subjectNoninvasive Ventilationen_US
dc.subjectSuccessen_US
dc.titleThe effect of acute kidney injury on the success of non-invasive ventilation in COPD patients with hypercapnic respiratory failureen_US
dc.typeArticleen_US

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