Antidepressants and menstruation disorders in women: a cross-sectional study in three centers

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dc.contributor.authorUguz, Faruk
dc.contributor.authorSahingoz, Mine
dc.contributor.authorKose, Seyit Ali
dc.contributor.authorOzbebit, Ozgur
dc.contributor.authorSengul, Cem
dc.contributor.authorSelvi, Yavuz
dc.contributor.authorSengul, Ceyhan Balci
dc.date.accessioned2024-02-23T14:02:59Z
dc.date.available2024-02-23T14:02:59Z
dc.date.issued2012
dc.departmentNEÜen_US
dc.description.abstractObjective: The relationship between menstruation disorders and antidepressant drugs usage in women remains unclear. In this study, we aimed to investigate the incidence rate of antidepressant-related menstruation disorders and to examine whether or not antidepressant use is associated with menstrual disorders in women. Methods: The study sample was gathered from three centers and four hospitals. A total of 1432 women who met the criteria of inclusion were included in the study. The sample was divided into two groups: the antidepressant group (n=793) and the control group (n=639). The menstruation disorders were established with reports from the study participants on the basis of related gynecological descriptions. Results: The prevalence of menstrual disorders was significantly higher in the antidepressant group (24.6%) than the control group (12.2%). The incidence of antidepressant-induced menstruation disorder was 14.5%. The antidepressants most associated with menstrual disorders were paroxetine, venlafaxine, sertraline and their combination with mirtazapine. Overall, the incidence rate was similar in women receiving selective serotonin reuptake inhibitors and serotonin noradrenaline reuptake inhibitors. Conclusions: The results of the present study suggest that menstruation disorders are frequently observed in women taking antidepressants and that it appears to be associated with antidepressant use at least in some women. (C) 2012 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.genhosppsych.2012.03.014
dc.identifier.endpage533en_US
dc.identifier.issn0163-8343
dc.identifier.issn1873-7714
dc.identifier.issue5en_US
dc.identifier.pmid22534402en_US
dc.identifier.scopus2-s2.0-84865367677en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage529en_US
dc.identifier.urihttps://doi.org/10.1016/j.genhosppsych.2012.03.014
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11926
dc.identifier.volume34en_US
dc.identifier.wosWOS:000308511500012en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofGeneral Hospital Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titleAntidepressants and menstruation disorders in women: a cross-sectional study in three centersen_US
dc.typeArticleen_US

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