Prognostic value of Tpeak-Tend interval in patients with acute pulmonary embolism

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dc.contributor.authorIcli, Abdullah
dc.contributor.authorKayrak, Mehmet
dc.contributor.authorAkilli, Hakan
dc.contributor.authorAribas, Alpay
dc.contributor.authorCoskun, Mukremin
dc.contributor.authorOzer, Sumeyye Fatma
dc.contributor.authorOzdemir, Kurtulus
dc.date.accessioned2024-02-23T14:27:17Z
dc.date.available2024-02-23T14:27:17Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractBackground: The aim of this study was to examine the Tpeak-Tend (Tpe/corrected Tpe) interval, which is an indicator of transmural myocardial repolarization, measured non-invasively via electrocardiogram in patients with acute pulmonary embolism (PE), and to investigate the relationship with 30-day mortality and morbidity. Methods: The study included 272 patients diagnosed with acute PE, comprising 154 females and 118 males, with a mean age of 63.1 +/- 16.8 years. Tpe/cTpe intervals were calculated from the electrocardiograms with a computer program after using a ruler or vernier caliper manual measuring tool to obtain highly sensitive measurements. The relationship between the electrocardiogram values and 30-days mortality and morbidity were measured. Results: The study group was divided into three groups according to cTpe intervals: Group 1, < 113 ms; Group 2, 113-133 ms; and Group 3, > 133 ms. White blood cell count and troponin T levels, corrected QT intervals with QRS complex durations, percentage of right ventricle dilatation with right/left-ventricular ratio, 30-day death, and combinations of these values were seen at a higher rate in Group 3 patients compared to the other groups. Kaplan-Meier analysis showed that the cTpe interval measured at > 126 ms could be used as a cut-off value in the prediction of mortality and morbidity. The cTpe cut-off values of 126 ms had sensivity, specificity, negative predictive value, and positive predictive value of 80.56 %, 59.32 %, 95.2 %, and 23.2 %, respectively. Conclusions: cTpe interval could be a useful method in early risk stratification in patients with acute PE.en_US
dc.identifier.doi10.1186/s12872-015-0091-4
dc.identifier.issn1471-2261
dc.identifier.pmid26335802en_US
dc.identifier.scopus2-s2.0-84940563940en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1186/s12872-015-0091-4
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14530
dc.identifier.volume15en_US
dc.identifier.wosWOS:000360425900001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBiomed Central Ltden_US
dc.relation.ispartofBmc Cardiovascular Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titlePrognostic value of Tpeak-Tend interval in patients with acute pulmonary embolismen_US
dc.typeArticleen_US

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