Peri-implant crevicular fluid levels of cathepsin-K, RANKL, and OPG around standard, short, and mini dental implants after prosthodontic loading

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dc.contributor.authorAlan, Raif
dc.contributor.authorMarakoglu, Ismail
dc.contributor.authorHaliloglu, Seyfullah
dc.date.accessioned2024-02-23T14:40:53Z
dc.date.available2024-02-23T14:40:53Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractPurpose: Despite the high success rates of endosseous dental implants, their placement is restricted according to the height and volume of bone available. The use of short or mini dental implants could be one way to overcome this limitation. Thus, this study aimed to compare standard, short, and mini dental implants with regard to associated clinical parameters and pen-implant crevicular fluid (PICF) levels of cathepsin-K (CTSK), RANK ligand (RANKL), and osteoprotegerin (UPS), after prosthodontic loading. Methods: A total of 78 non-submerged implants (Euroteknika, Aesthetica(+2), Sallanches, France) were installed in 30 subjects (13 male, 17 female; range, 26-62 years) who visited the clinic of the Periodontology Department Faculty of Dentistry, Selcuk University. Sampling and measurements were performed on the loading date (baseline) and 2, 14, and 90 days after loading. Assessment of the pen-implant status for the implant sites was performed using the pocket probing depth (PPD), modified plaque index, modified gingival index, modified sulcular bleeding index, and radiographic signs of bone loss. PICF samples collected from each implant were evaluated for CTSK, RANKL, and UPS levels using the ELISA method. Keratinized tissue and marginal bone loss (MBL) were also noted. Results: Clinical parameters statistically significantly increased in each group but did not show statistical differences between groups without PPD. Although implant groups showed a higher MBL in the upper jaw, only the standard dental group demonstrated a statistically significant difference. At 90 days, the OPG:sRANKL ratio and total amounts of CTSK for each group did not differ from baseline. Conclusions: Within the limitations of this study, both short and mini dental implants were achieving the same outcomes as the standard dental implants in the early period after loading.en_US
dc.description.sponsorshipSelcuk University; Latek Medikal (Istanbul,Turkey)en_US
dc.description.sponsorshipThe authors would like to thank the Scientific Research Projects Coordinator of Selcuk University for funding this research and Dr. Akdogan and Dr. Unal for statistical advice. Dental implants applied in this study were also supported by a grant from Latek Medikal (Istanbul,Turkey).en_US
dc.identifier.doi10.5051/jpis.2015.45.5.169
dc.identifier.endpage177en_US
dc.identifier.issn2093-2278
dc.identifier.issn2093-2286
dc.identifier.issue5en_US
dc.identifier.pmid26550525en_US
dc.identifier.scopus2-s2.0-84946564603en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage169en_US
dc.identifier.urihttps://doi.org/10.5051/jpis.2015.45.5.169
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16630
dc.identifier.volume45en_US
dc.identifier.wosWOS:000365378200003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKorean Acad Periodontologyen_US
dc.relation.ispartofJournal Of Periodontal And Implant Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAlveolar Bone Lossen_US
dc.subjectCathepsin Ken_US
dc.subjectDental Implantsen_US
dc.subjectOsteoprotegerinen_US
dc.subjectRank Liganden_US
dc.titlePeri-implant crevicular fluid levels of cathepsin-K, RANKL, and OPG around standard, short, and mini dental implants after prosthodontic loadingen_US
dc.typeArticleen_US

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