Dapsone for the treatment of acne vulgaris: do the risks outweigh the benefits?

Basit Öğe Kaydı
dc.contributor.authorTemiz, Selami Aykut
dc.contributor.authorDaye, Munise
dc.date.accessioned2024-02-23T14:20:42Z
dc.date.available2024-02-23T14:20:42Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractDapsone is a 4,4'-diamino diphenyl sulfone compound and an aniline derivative from synthetic sulphones. Sulphonamides were first used in humans as antimicrobial agents to treat streptococcal infections. Dapsone derived from sulphonamides was first used in the treatment of leprosy in 1940. Today, Dapsone treatment is among the treatment options for many dermatological diseases. Acne vulgaris is a chronic inflammatory disease, which causes scar formation and changed pigmentation. Acne affects 85% of teenagers, but can occur at any age and can last into adulthood and even lifelong. Through its antimicrobial, anti-inflammatory, and antioxidant effects, dapsone treatment (local or systemic) can also be used in the treatment of acne. Dapsone treatment can cause a variety of side effects that can be categorized as pharmacological, dose-related, allergic, or idiosyncratic reactions. In this review article, the risks and benefits of using dapsone treatment in acne vulgaris will be evaluated in light of the literature.en_US
dc.identifier.doi10.1080/15569527.2021.2024565
dc.identifier.endpage66en_US
dc.identifier.issn1556-9527
dc.identifier.issn1556-9535
dc.identifier.issue1en_US
dc.identifier.pmid34969324en_US
dc.identifier.scopus2-s2.0-85122756003en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage60en_US
dc.identifier.urihttps://doi.org/10.1080/15569527.2021.2024565
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13253
dc.identifier.volume41en_US
dc.identifier.wosWOS:000740920400001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofCutaneous And Ocular Toxicologyen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDapsoneen_US
dc.subjectAcneen_US
dc.subjectSafetyen_US
dc.subjectSystemicen_US
dc.subjectLocalen_US
dc.subjectIsotretinoinen_US
dc.titleDapsone for the treatment of acne vulgaris: do the risks outweigh the benefits?en_US
dc.typeEditorial Materialen_US

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