Power Reflectance as a Screening Tool for the Diagnosis of Superior Semicircular Canal Dehiscence

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dc.contributor.authorMerchant, Gabrielle R.
dc.contributor.authorRoeoesli, Christof
dc.contributor.authorNiesten, Marlien E. F.
dc.contributor.authorHamade, Mohamad A.
dc.contributor.authorLee, Daniel J.
dc.contributor.authorMcKinnon, Melissa L.
dc.contributor.authorUlku, Cagatay H.
dc.date.accessioned2024-02-23T14:48:43Z
dc.date.available2024-02-23T14:48:43Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractHypothesis: Power reflectance (PR) measurements in ears with superior canal dehiscence (SCD) have a characteristic pattern, the detection of which can assist in diagnosis. Background: The aim of this study was to determine whether PR coupled with a novel detection algorithm can perform well as a fast, noninvasive, and easy screening test for SCD. The screening test aimed to determine whether patients with various vestibular and/or auditory symptom(s) should be further considered for more expensive and invasive tests that better define the diagnosis of SCD (and other third-window lesions). Methods: Power reflectance was measured in patients diagnosed with SCD by high-resolution computed tomography. The study included 40 ears from 32 patients with varying symptoms (e.g., with and without conductive hearing loss, vestibular symptoms, and abnormal auditory sensations). Results: Power reflectance results were compared to previously published norms and showed that SCD is commonly associated with a PR notch near 1 kHz. An analysis algorithm was designed to detect such notches and to quantify their incidence in affected and normal ears. Various notch detection thresholds yielded sensitivities of 80% to 93%, specificities of 69% to 72%, negative predictive values of 84% to 93%, and a positive predictive value of 67%. Conclusion: This study shows evidence that PR measurements together with the proposed notch-detecting algorithm can be used to quickly and effectively screen patients for third-window lesions such as SCD in the early stages of a diagnostic work up.en_US
dc.description.sponsorshipNachwuchsforderungskredit of the University of Zurich; TUBITAK; National Institutes of Health/National Institute on Deafness and Other Communication Disorders [R01DC004790, R03DC011158]en_US
dc.description.sponsorshipThis study was made possible owing to support from the Nachwuchsforderungskredit of the University of Zurich (C. R.), TUBITAK (C. H. U.), and the National Institutes of Health/National Institute on Deafness and Other Communication Disorders (R01DC004790 to S. N. M. and R03DC011158 to H. H. N.).en_US
dc.identifier.endpage177en_US
dc.identifier.issn1531-7129
dc.identifier.issn1537-4505
dc.identifier.issue1en_US
dc.identifier.pmid25076227en_US
dc.identifier.scopus2-s2.0-84919479052en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage172en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12452/17803
dc.identifier.volume36en_US
dc.identifier.wosWOS:000346368200033en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofOtology & Neurotologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdmittanceen_US
dc.subjectEnergy Reflectanceen_US
dc.subjectPower Reflectanceen_US
dc.subjectReflectanceen_US
dc.subjectSuperior Canal Dehiscenceen_US
dc.subjectSuperior Semicircular Canal Dehiscenceen_US
dc.subjectWideband Acoustic Immittanceen_US
dc.titlePower Reflectance as a Screening Tool for the Diagnosis of Superior Semicircular Canal Dehiscenceen_US
dc.typeArticleen_US

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