Preparation of lysozyme loaded gelatin microcryogels and investigation of their antibacterial properties

Basit Öğe Kaydı
dc.contributor.authorCetin, Kemal
dc.contributor.authorAsliyuce, Sevgi
dc.contributor.authorIdil, Neslihan
dc.contributor.authorDenizli, Adil
dc.date.accessioned2024-02-23T14:20:17Z
dc.date.available2024-02-23T14:20:17Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractAntibacterial micron-sized cryogels, so-called microcryogels, were prepared by cryogelation of gelatin and integration of lysozyme. Gelation yield, specific surface area, macro-porosity and swelling degree of the microcryogels were examined in order to characterize their physical properties. MTT method was utilized to measure cell viability of the gelatin microcryogels with a period of 24, 48, and 72 h and no significant decrease was observed at 72 h. Apoptotic staining assay also showed high viability at 24, 48, 72 h in parallel with the control group. The antibacterial performances of the gelatin microcryogels againstBacillus subtilis,Staphylococcus aureus,andEscherichia coliwere examined. The results showed that the incorporation of lysozyme into gelatin microcryogels exhibited the antibacterial activity againstS. aureus, B. subtilis, andE. coli, that may provide great potential for various applications in the biomedical industry.en_US
dc.description.sponsorshipHacettepe University, Scientific Research Projects Coordination Unit, Ankara Turkey [FHD-2017-14417]en_US
dc.description.sponsorshipThis study was supported by Hacettepe University, Scientific Research Projects Coordination Unit, Ankara Turkey (Grant number: FHD-2017-14417).en_US
dc.identifier.doi10.1080/09205063.2020.1825303
dc.identifier.endpage204en_US
dc.identifier.issn0920-5063
dc.identifier.issn1568-5624
dc.identifier.issue2en_US
dc.identifier.pmid32962559en_US
dc.identifier.scopus2-s2.0-85092084254en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage189en_US
dc.identifier.urihttps://doi.org/10.1080/09205063.2020.1825303
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13106
dc.identifier.volume32en_US
dc.identifier.wosWOS:000575766300001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal Of Biomaterials Science-Polymer Editionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntibacterialen_US
dc.subjectDegradableen_US
dc.subjectLysozymeen_US
dc.subjectMicrocryogelsen_US
dc.titlePreparation of lysozyme loaded gelatin microcryogels and investigation of their antibacterial propertiesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu