Predicting protein-protein interactions by weighted pseudo amino acid composition

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dc.contributor.authorGoktepe, Yunus Emre
dc.contributor.authorIlhan, Ilhan
dc.contributor.authorKahramanli, Sirzat
dc.date.accessioned2024-02-23T14:29:43Z
dc.date.available2024-02-23T14:29:43Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractProtein-protein interactions hold very important roles in biological processes. Prediction of PPIs is important for understanding these processes. In this context, substantive representations of proteins are needed during the process of interaction prediction in order to achieve higher prediction accuracy. In this paper, a new feature representation method, based on the concept of Chou's pseudo amino acid composition, was introduced. It is composed of the weighted amino acid composition information and the correlation factors of the protein. Finally, an SVM classification model was constructed for predicting PPIs. Experimental results exhibit that our method precedes those previously published in the literature.en_US
dc.identifier.doi10.1504/IJDMB.2016.077073
dc.identifier.endpage290en_US
dc.identifier.issn1748-5673
dc.identifier.issn1748-5681
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84975840889en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage272en_US
dc.identifier.urihttps://doi.org/10.1504/IJDMB.2016.077073
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14833
dc.identifier.volume15en_US
dc.identifier.wosWOS:000378614300005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherInderscience Enterprises Ltden_US
dc.relation.ispartofInternational Journal Of Data Mining And Bioinformaticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectProtein-Protein Interactionen_US
dc.subjectProtein Feature Extractionen_US
dc.subjectPseudo Amino Acid Compositionen_US
dc.subjectSupport Vector Machinesen_US
dc.titlePredicting protein-protein interactions by weighted pseudo amino acid compositionen_US
dc.typeArticleen_US

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