Is intra-articular magnesium effective for postoperative analgesia in arthroscopic shoulder surgery?

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dc.contributor.authorSaritas, Tuba Berra
dc.contributor.authorBorazan, Hale
dc.contributor.authorOkesli, Selmin
dc.contributor.authorYel, Mustafa
dc.contributor.authorOtelcioglu, Seref
dc.date.accessioned2024-02-23T14:26:30Z
dc.date.available2024-02-23T14:26:30Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractBACKGROUND: Various medications are used intra-articularly for postoperative pain reduction after arthroscopic shoulder surgery. Magnesium, a N-methyl-D-aspartate receptor antagonist, may be effective for reduction of both postoperative pain scores and analgesic requirements. METHODS: A total of 67 patients undergoing arthroscopic shoulder surgery were divided randomly into two groups to receive intra-articular injections of either 10 mL magnesium sulphate (100 mg/mL; group M, n=34) or 10 mL of normal saline (group C, n= 33). The analgesic effect was estimated using a visual analogue scale 1 h, 2 h, 6 h, 8 h, 12 h, 18 h and 24 h after operation. Postoperative analgesia was maintained by intra-articular morphine (0.01%, 10 mg) + bupivacaine (0.5%, 100 mL) patient-controlled analgesia device as a 1 mL infusion with a 1 mL bolus dose and 15 min lock-out time; for visual analogue scale scores > 5, intramuscular diclofenac sodium 75 mg was administered as needed during the study period (maximum two times). RESULDS: Intra-articular magnesium resulted in a significant reduction in pain scores in group M compared with group C 1 h, 2 h, 6 h, 8 h and 12 h after the end of surgery, respectively, at rest and with passive motion. Total diclofenac consumption and intra-articular morphine + bupivacaine consumption were significantly lower in group M. Postoperative serum magnesium levels were significantly higher in group M, but were within the normal range. CONCLUSION: Magnesium causes a reduction in postoperative pain in comparison to saline when administered intra-articularly after arthroscopic shoulder surgery, and has no serious side effects.en_US
dc.identifier.doi10.1155/2015/648063
dc.identifier.endpage38en_US
dc.identifier.issn1203-6765
dc.identifier.issn1918-1523
dc.identifier.issue1en_US
dc.identifier.pmid25222574en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage35en_US
dc.identifier.urihttps://doi.org/10.1155/2015/648063
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14225
dc.identifier.volume20en_US
dc.identifier.wosWOS:000351715700005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPulsus Group Incen_US
dc.relation.ispartofPain Research & Managementen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBupivacaineen_US
dc.subjectIntra-Articularen_US
dc.subjectMagnesiumen_US
dc.subjectMorphineen_US
dc.subjectPatient-Controlled Analgesiaen_US
dc.titleIs intra-articular magnesium effective for postoperative analgesia in arthroscopic shoulder surgery?en_US
dc.typeArticleen_US

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