The comparison of the degree of apoptosis in ovaries and fallopian tubes between two different surgical interventions for tubal ligation: A rat model

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dc.contributor.authorMumusoglu, Sezcan
dc.contributor.authorHacivelioglu, Servet
dc.contributor.authorSokmensuer, Lale Karakoc
dc.contributor.authorKaratayli, Rengin
dc.contributor.authorSuzer, Aysegul
dc.contributor.authorKaymaz, Figen
dc.date.accessioned2024-02-23T14:38:10Z
dc.date.available2024-02-23T14:38:10Z
dc.date.issued2018
dc.departmentNEÜen_US
dc.description.abstractObjective: To compare the degree of apoptosis in ovaries and tubal epithelium observed secondary to tubal ligation either by Pomeroy's method or bipolar electrocauterization in a rat model. Material and Methods: A total of 24 female Sprague-Dawley rats were randomly assigned into 3 study groups: control (n=8), Pomeroy (n=8), and the electrocauterization group (n=8). Apoptotic cells were detected on the primary, secondary, tertiary follicles of the ovaries, and on the tubal epithelium using terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end-labeling. The apoptotic index was calculated for each group by the percentage of the stained cells. Results: The apoptotic index of tubal epithelium was significantly higher in the bipolar electrocauterization group compared with the control and Pomeroy groups (3.1 +/- 0.8 vs. 1.4 +/- 1.0, p=0.018 and 2.0 +/- 1.2, p=0.03, respectively) whereas there was no significant difference between Pomeroy's method and the control group. The apoptotic index of primary follicles was higher in the bipolar electrocauterization group compared with the control and Pomeroy's method groups (3.4 +/- 0.5 vs. 1.2 +/- 0.4, p<0.001 and 1.8 +/- 0.8, p=0.005, respectively), but there was no significant difference between Pomeroy's method and the control group. The apoptotic index of secondary and tertiary follicles was similar for each group. Conclusion: Pomeroy's technique, as a permanent contraception method, is associated with lower apoptotic index on ovary and fallopian tube when compared with bipolar electrocauterization.en_US
dc.identifier.doi10.4274/jtgga.2016.0192
dc.identifier.endpage16en_US
dc.identifier.issn1309-0399
dc.identifier.issn1309-0380
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85045200686en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage11en_US
dc.identifier.urihttps://doi.org/10.4274/jtgga.2016.0192
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16404
dc.identifier.volume19en_US
dc.identifier.wosWOS:000426433200004en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofJournal Of The Turkish-German Gynecological Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTubal Ligationen_US
dc.subjectBipolar Electrocauterizationen_US
dc.subjectPomeroyen_US
dc.subjectOvarian Reserveen_US
dc.subjectFallopian Tubeen_US
dc.titleThe comparison of the degree of apoptosis in ovaries and fallopian tubes between two different surgical interventions for tubal ligation: A rat modelen_US
dc.typeArticleen_US

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