Effect of mydriasis induced by topical 0.5% tropicamide instillation on the corneal biomechanical properties in healthy individuals measured by ocular response analyzer

dc.contributor.authorOltulu, Refik
dc.contributor.authorSatirtav, Gunhal
dc.contributor.authorAltunkaya, Orhan
dc.contributor.authorBitirgen, Gulfidan
dc.contributor.authorOkka, Mehmet
dc.date.accessioned2024-02-23T14:34:39Z
dc.date.available2024-02-23T14:34:39Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractPurpose: This observational study aims to investigate the effects of tropicamide (0.5%) on corneal biomechanical properties, with the ocular response analyzer (ORA), in healthy individuals. Methods: Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal-compensated intraocular pressure (IOPcc) measurements of 38 (21 female and 17 male) healthy individuals, before and after 30 min of 0.5% tropicamide instillation, were performed by using the ORA. Results: The mean CH, CRF, IOPg and IOPcc measurements of the eyes were 10.2 +/- 1.9 mmHg, 10.3 +/- 2.1 mmHg, 15.7 +/- 3.4 mmHg, 16.4 +/- 3.3 mmHg pre-tropicamide, and 10.4 +/- 1.7 mmHg, 10.3 +/- 2.1 mmHg, 15.3 +/- 3.4 mmHg, 15.8 +/- 2.7 mmHg post-tropicamide, respectively. The differences between the pre- and post-tropicamide measurements of the eyes were insignificant (p = 0.184, p = 0.659, p = 0.294, p = 0.150, respectively; paired t-test). Conclusions: A tropicamide instillation does not lead to significant changes in the corneal biomechanical properties. Therefore, it can be used safely in disease, i.e. in the diagnosis and follow-up ORA as it does not cause any change.en_US
dc.identifier.doi10.3109/15569527.2014.883404
dc.identifier.endpage37en_US
dc.identifier.issn1556-9527
dc.identifier.issn1556-9535
dc.identifier.issue1en_US
dc.identifier.pmid24678749en_US
dc.identifier.scopus2-s2.0-84925308036en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage35en_US
dc.identifier.urihttps://doi.org/10.3109/15569527.2014.883404
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15688
dc.identifier.volume34en_US
dc.identifier.wosWOS:000351309900007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofCutaneous And Ocular Toxicologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCorneal Biomechanicsen_US
dc.subjectOcular Response Analyzeren_US
dc.subjectTropicamideen_US
dc.titleEffect of mydriasis induced by topical 0.5% tropicamide instillation on the corneal biomechanical properties in healthy individuals measured by ocular response analyzeren_US
dc.typeArticleen_US

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