The association of total sialic acid and malondialdehyde levels with metabolic and anthropometric variables in obesity

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dc.contributor.authorYerlikaya, F. H.
dc.contributor.authorToker, A.
dc.contributor.authorCicekler, H.
dc.contributor.authorAribas, A.
dc.date.accessioned2024-02-23T14:34:37Z
dc.date.available2024-02-23T14:34:37Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractSerum sialic acid levels are abnormally high in pathological states that exhibit tissue destruction, tissue proliferation or inflammation. We measured total serum sialic acid levels in 139 women and 125 men. Subjects were divided into quartiles according to their body mass index (BMI): Q1 (18-24.9 kg/m(2)), Q2 (25 -29.9 kg/m(2)), Q3 (30 -39.9 kg/m(2)) and Q4 (> 40 kg/m(2)). The patients in Q1 constituted the control group. Serum sialic acid levels of subjects in Q2, Q3 and Q4 were signifi cantly higher than those in Q1. Higher BMI quartiles also were associated with higher levels of serum glucose, insulin, total cholesterol, LDL-cholesterol, triglycerides, high-sensitivity C-reactive protein, malondialdehyde levels, waist circumference, blood pressure and homeostasis model assessment of insulin resistance in both women and men. Lower BMI quartiles were associated with higher levels of serum HDL-cholesterol levels in both women and men. We found positive associations among serum sialic acid levels, BMI and oxidative stress. Serum sialic acid also is related to some conventional cardiovascular risk factors including elevated lipid profile, increased blood pressure, increased serum glucose and insulin levels, and insulin resistance in obese people.en_US
dc.identifier.doi10.3109/10520295.2014.937744
dc.identifier.endpage37en_US
dc.identifier.issn1052-0295
dc.identifier.issn1473-7760
dc.identifier.issue1en_US
dc.identifier.pmid25151992en_US
dc.identifier.scopus2-s2.0-84919459218en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage31en_US
dc.identifier.urihttps://doi.org/10.3109/10520295.2014.937744
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15675
dc.identifier.volume90en_US
dc.identifier.wosWOS:000351942200005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBiotechnic & Histochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBody Mass Indexen_US
dc.subjectCardiovascular Risken_US
dc.subjectObesityen_US
dc.subjectOxidative Stressen_US
dc.subjectSialic Aciden_US
dc.titleThe association of total sialic acid and malondialdehyde levels with metabolic and anthropometric variables in obesityen_US
dc.typeArticleen_US

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