Clinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Months After a Diagnosis of COVID-19

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dc.contributor.authorDuivenvoorden, Raphael
dc.contributor.authorVart, Priya
dc.contributor.authorNoordzij, Marlies
dc.contributor.authorSoares dos Santos, Augusto C., Jr.
dc.contributor.authorZulkarnaev, Alex B.
dc.contributor.authorFranssen, Casper F. M.
dc.contributor.authorKuypers, Dirk
dc.date.accessioned2024-02-23T14:23:31Z
dc.date.available2024-02-23T14:23:31Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractBackground. Kidney transplant patients are at high risk for coronavirus disease 2019 (COVID-19)-related mortality. However, limited data are available on longer-term clinical, functional, and mental health outcomes in patients who survive COVID-19. Methods. We analyzed data from adult kidney transplant patients in the European Renal Association COVID-19 Database who presented with COVID-19 between February 1, 2020, and January 31, 2021. Results. We included 912 patients with a mean age of 56.7 (+/- 13.7) y. 26.4% were not hospitalized, 57.5% were hospitalized without need for intensive care unit (ICU) admission, and 16.1% were hospitalized and admitted to the ICU. At 3 mo follow-up survival was 82.3% overall, and 98.8%, 84.2%, and 49.0%, respectively, in each group. At 3 mo follow-up biopsy-proven acute rejection, need for renal replacement therapy, and graft failure occurred in the overall group in 0.8%, 2.6%, and 1.8% respectively, and in 2.1%, 10.6%, and 10.6% of ICU-admitted patients, respectively. Of the surviving patients, 83.3% and 94.4% reached their pre-COVID-19 physician-reported functional and mental health status, respectively, within 3 mo. Of patients who had not yet reached their prior functional and mental health status, their treating physicians expected that 79.6% and 80.0%, respectively, still would do so within the coming year. ICU admission was independently associated with a low likelihood to reach prior functional and mental health status. Conclusions. In kidney transplant recipients alive at 3-mo follow-up, clinical, physician-reported functional, and mental health recovery was good for both nonhospitalized and hospitalized patients. Recovery was, however, less favorable for patients who had been admitted to the ICU.en_US
dc.description.sponsorshipERA-EDTA; Baxter; Sandoz; Dutch Kidney Foundationen_US
dc.description.sponsorshipERACODA received unrestricted research grants from ERA-EDTA, The Dutch Kidney Foundation, Baxter, and Sandoz.en_US
dc.identifier.doi10.1097/TP.0000000000004075
dc.identifier.endpage1023en_US
dc.identifier.issn0041-1337
dc.identifier.issn1534-6080
dc.identifier.issue5en_US
dc.identifier.pmid35320154en_US
dc.identifier.scopus2-s2.0-85128844539en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1012en_US
dc.identifier.urihttps://doi.org/10.1097/TP.0000000000004075
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13590
dc.identifier.volume106en_US
dc.identifier.wosWOS:000787290500035en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofTransplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titleClinical, Functional, and Mental Health Outcomes in Kidney Transplant Recipients 3 Months After a Diagnosis of COVID-19en_US
dc.typeArticleen_US

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