Investigation of Relaxin-3 Serum Levels in terms of Social Interaction, Communication, and Appetite as a Biomarker in Children with Autism

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dc.contributor.authorErden, Semih
dc.contributor.authorNalbant, Kevser
dc.contributor.authorKilinc, Ibrahim
dc.date.accessioned2024-02-23T14:44:57Z
dc.date.available2024-02-23T14:44:57Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractObjective: To investigate the possible relationship between relaxin-3 and autism spectrum disorder (ASD). Methods: Serum relaxin-3 was measured in 80 children (50 children diagnosed with ASD and 30 controls). Symptom severity in the ASD group was evaluated by the Childhood Autism Rating Scale (CARS). Behavioral and nutritional problems in the groups were evaluated using the Abnormal Behavior Checklist (ABC) and the Children & apos;s Eating Behavior Results: Our findings showed that serum relaxin-3 levels were higher in children with ASD than in the controls. The listening response sub-scale score of the CARS scale was found to decrease as the level of relaxin-3 increased. However, as relaxin-3 levels increased in children with ASD, it was found that the speech problem sub-scale score on the ABC scale and the desire to drink score on the CEBQ scale increased, but the satiety responsiveness and food fussiness scores decreased. Conclusion: This study the first to investigate serum levels of relaxin-3, which has a role in regulating social behavior and nutritional behavior in children with ASD.en_US
dc.identifier.doi10.9758/cpn.2022.20.1.135
dc.identifier.endpage142en_US
dc.identifier.issn1738-1088
dc.identifier.issn2093-4327
dc.identifier.issue1en_US
dc.identifier.pmid35078956en_US
dc.identifier.scopus2-s2.0-85124458939en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage135en_US
dc.identifier.urihttps://doi.org/10.9758/cpn.2022.20.1.135
dc.identifier.urihttps://hdl.handle.net/20.500.12452/17169
dc.identifier.volume20en_US
dc.identifier.wosWOS:000748009300004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKorean Coll Neuropsychopharmacologyen_US
dc.relation.ispartofClinical Psychopharmacology And Neuroscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectKey Wordsen_US
dc.subjectAutism Spectrum Disorderen_US
dc.subjectCommunicationen_US
dc.subjectAppetiteen_US
dc.subjectRelaxinen_US
dc.titleInvestigation of Relaxin-3 Serum Levels in terms of Social Interaction, Communication, and Appetite as a Biomarker in Children with Autismen_US
dc.typeArticleen_US

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