Refractory Urticarial Vasculitis Responsive to Methotrexate: Could It Be a New Treatment Option?

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dc.contributor.authorTemiz, Selami Aykut
dc.contributor.authorAtaseven, Arzu
dc.contributor.authorOzer, Ilkay
dc.contributor.authorDursun, Recep
dc.contributor.authorFindik, Siddika
dc.date.accessioned2024-02-23T14:34:55Z
dc.date.available2024-02-23T14:34:55Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractObjective: Urticarial vasculitis is a chronic clinicopathologic entity characterized by clinically characterized urticarial rash, histopathologically characterized by leukocytoclastic vasculitis. The pathogenesis is thought to be developed by a type III hypersensitivity reaction similar to leukocytoclastic vasculitis. Methods: Antihistamines and/or corticosteroids (systemic/local) may be used in patients with limited normocomplementemic urticarial vasculitis. In the literature, severe cases treated with dapsone, colchicine, hydroxychloroquine, pentoxifylline, omalizumab, mycophenolate mofetil, rituximab, cyclosporine, intravenous immunoglobulin, and cyclophosphamide have been reported in the case reports. Results: In this case, the patient, whose symptoms had not previously responded to treatment with antihistamines, steroids, cyclosporine, and omalizumab, responded to treatment with methotrexate. Conclusion: This case report recommends that methotrexate therapy may be a treatment option for cases of resistant urticarial vasculitis.en_US
dc.identifier.doi10.33808/marusbed.546841
dc.identifier.endpage95en_US
dc.identifier.issn2459-1459
dc.identifier.issue1en_US
dc.identifier.startpage93en_US
dc.identifier.urihttps://doi.org/10.33808/marusbed.546841
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15816
dc.identifier.volume9en_US
dc.identifier.wosWOS:000462818200015en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherMarmara Univ, Inst Health Sciencesen_US
dc.relation.ispartofClinical And Experimental Health Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectUrticarial Vasculitisen_US
dc.subjectMethotrexateen_US
dc.subjectOmalizumaben_US
dc.titleRefractory Urticarial Vasculitis Responsive to Methotrexate: Could It Be a New Treatment Option?en_US
dc.typeArticleen_US

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