Which metabolic syndrome criteria best predict non-alcoholic fatty liver disease in children?

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dc.contributor.authorAtabek, Mehmet Emre
dc.contributor.authorEklioglu, Beray Selver
dc.contributor.authorAkyurek, Nesibe
dc.date.accessioned2024-02-23T14:00:10Z
dc.date.available2024-02-23T14:00:10Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractObjective The aim of this study was to identify which metabolic syndrome criteria (WHO or IDF) better reflect the presence of non-alcoholic fatty liver disease (NAFLD) and to determine the prevalence of metabolic syndrome (MS) and NAFLD. Methods Two hundred and seventeen obese children and adolescents, 8-15 years of age (body mass index > 95 p), were included in the study. Anthropometric measurements, blood pressure measurements, an oral glucose tolerance test and lipid profile were measured. MS was diagnosed according to WHO and IDF criteria. NAFLD risk ratio was assessed according to the two MS criteria. Results The prevalence of MS according to the IDF criteria was 43.3 %, and according to WHO criteria it was 55.2 %. NAFLD prevalence in the metabolic syndrome group according to IDF criteria was 25.5 % and this was statistically significant (p = 0.007). The prevalence of NAFLD was 20.8 % in the group with MS according to WHO criteria and this was not a statistically significant difference (p = 0.15). NAFLD hazard ratios were 7.06 (95 % CI 1.29-5.50) in the MS group according to IDF criteria and 2.02 (95 % CI 0.81-3.53) in the group with metabolic syndrome according to WHO criteria. IDF criteria were found to have a higher odds ratio. Conclusion The prevalence of MS depends on the diagnostic criteria used. IDF criteria give the best measure for the presence of NAFLD. NAFLD might be important as diagnostic criterion for MS.en_US
dc.identifier.doi10.1007/s40519-014-0129-0
dc.identifier.endpage501en_US
dc.identifier.issn1124-4909
dc.identifier.issn1590-1262
dc.identifier.issue4en_US
dc.identifier.pmid24844310en_US
dc.identifier.scopus2-s2.0-84920148693en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage495en_US
dc.identifier.urihttps://doi.org/10.1007/s40519-014-0129-0
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11483
dc.identifier.volume19en_US
dc.identifier.wosWOS:000344756600007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEating And Weight Disorders-Studies On Anorexia Bulimia And Obesityen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectObesityen_US
dc.subjectMetabolic Syndromeen_US
dc.subjectNon-Alcoholic Fatty Liver Diseaseen_US
dc.subjectChildrenen_US
dc.titleWhich metabolic syndrome criteria best predict non-alcoholic fatty liver disease in children?en_US
dc.typeArticleen_US

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