Peripartum hemorrhage and other obstetric and neonatal outcomes in pregnant women with epilepsy: A single-center study

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dc.contributor.authorIsikalan, Mehmet Murat
dc.contributor.authorGundogan, Kubra Memnune
dc.contributor.authorAcar, Ali
dc.date.accessioned2024-02-23T14:02:52Z
dc.date.available2024-02-23T14:02:52Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractObjective: There are inconsistent results in different studies on maternal and fetal complications of pregnant women with epilepsy (PWWE). The differences may be in part due to racial characteristics. The aim of this study was to investigate if there is an increase in obstetric and neonatal complications, especially postpartum hemorrhage, in pregnant women with epilepsy in the Turkish population. Methods: In a tertiary center, PWWE and the control group were compared in terms of obstetric and neonatal complications as well as postpartum hemorrhage. Among 46,789 deliveries, 154 eligible PWWE were matched 1: 3 with the control group. Results: There was no increase in the possibility of peripartum hemorrhage and blood transfusion in PWWE. However, the probability of cesarean delivery was higher in PWWE (adjusted OR: 3.24 CI: 1.95?5.42, p < 0.001). Moreover, an increase in the possibility of fetal growth restriction, fetal death, admission to the neonatal intensive care unit and lower APGAR scores were found in PWWE. Conclusion: Although the risk of peripartum hemorrhage does not appear to be increased in PWWE, cesarean rates and fetal complications do increase. There is also a need for prospective studies examining long-term neonatal outcomes in pregnancies complicated by epilepsy.en_US
dc.identifier.doi10.1016/j.eplepsyres.2021.106566
dc.identifier.issn0920-1211
dc.identifier.issn1872-6844
dc.identifier.pmid33524872en_US
dc.identifier.scopus2-s2.0-85099959631en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1016/j.eplepsyres.2021.106566
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11864
dc.identifier.volume171en_US
dc.identifier.wosWOS:000630967800001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofEpilepsy Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnti-Epileptic Drugsen_US
dc.subjectEpilepsyen_US
dc.subjectEpilepsy During Pregnancyen_US
dc.subjectPostpartum Hemorrhageen_US
dc.subjectPregnant Women With Epilepsyen_US
dc.titlePeripartum hemorrhage and other obstetric and neonatal outcomes in pregnant women with epilepsy: A single-center studyen_US
dc.typeArticleen_US

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