The Relationship Between Maternal Antidepressants and Neonatal Hypoglycemia: A Systematic Review

dc.contributor.authorUguz, Faruk
dc.date.accessioned2024-02-23T14:41:02Z
dc.date.available2024-02-23T14:41:02Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractThe aim of the article is to review systematically current researches investigating the relationship between intrauterine exposure to antidepressants and neonatal hypoglycemia. This paper included studies published in electronic databases from January 2005 to July 2020. The searched keywords were as follows: antidepressants, pregnancy, selective serotonin reuptake inhibitors (SSRIs), citalopram, fluoxetine, paroxetine, escitalopram, sertraline, fluvoxamine, selective serotonin-norepinephrine reuptake inhibitors (SNRIs), venlafaxine, tricyclic antidepressants (TCAs), neonatal outcomes, neonatal hypoglycemia, imipramine, clomipramine, amitriptyline, bupropion, trazodone, and mirtazapine. This review examined 10 relevant studies. The odds ratio/risk ratio reported in the studies were 1.33-1.73 for any antidepressant, 1.30-1.35 for SSRI, 1.42-2.11 for SNRI, and 2.07 for TCAs. The risk of neonatal hypoglycemia in infants exposed to maternal TCAs appears to be slightly higher compared to infants exposed to maternal SSRIs. Data from current studies consistently show that exposure to maternal antidepressants during pregnancy may be related to increased risk of neonatal hypoglycemia in infants.en_US
dc.identifier.doi10.5152/alphapsychiatry.2021.21143
dc.identifier.endpage229en_US
dc.identifier.issn2757-8038
dc.identifier.issue5en_US
dc.identifier.pmid36447450en_US
dc.identifier.scopus2-s2.0-85115628592en_US
dc.identifier.startpage224en_US
dc.identifier.urihttps://doi.org/10.5152/alphapsychiatry.2021.21143
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16674
dc.identifier.volume22en_US
dc.identifier.wosWOS:000695460800002en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofAlpha Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntidepressive Agentsen_US
dc.subjectHypoglycemiaen_US
dc.subjectPregnancyen_US
dc.subjectTherapeuticsen_US
dc.titleThe Relationship Between Maternal Antidepressants and Neonatal Hypoglycemia: A Systematic Reviewen_US
dc.typeReview Articleen_US

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