Predictive Value of Atrial Electromechanical Delay on Long-Term Cardiovascular Outcomes in Hemodialysis Patients

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dc.contributor.authorTurkmen, Kultigin
dc.contributor.authorDemirtas, Event
dc.contributor.authorTopal, Ergun
dc.contributor.authorGaipov, Abduzhappar
dc.contributor.authorKocyigit, Ismail
dc.contributor.authorOrscelik, Ozcan
dc.contributor.authorGuney, Ibrahim
dc.date.accessioned2024-02-23T14:26:39Z
dc.date.available2024-02-23T14:26:39Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractBackground: Atrial electromechanical delay (AEMD) times were considered independent predictors of cardiovascular morbidity among the general population. We aimed at evaluating AEMD times and other risk factors associated with 2-year combined cardiovascular (CV) events in HD patients. Material and Methods: Sixty hemodialysis (HD) and 44 healthy individuals were enrolled in this prospective study. Echocardiography was performed before the mid-week dialysis session for HD patients. Data were expressed as mean SD. Spearman test was used to assess linear associations. Survival was examined with the Kaplan-Meier method. Multivariate Cox regression analysis was used to determine the predictors of combined CV events in this cohort. Results: At the beginning of the study, left intra-atrial-AEMD times were significantly longer in HD patients compared to the left intra-atrial-AEMD times in healthy individuals. After 24 months, 41 patients were still on HD treatment and 19 (31.6%) had died. Serum triglyceride, total cholesterol and albumin were found to be higher and C-reactive protein (CRP) levels, left intra-atrial EMD time (LIAT) and interatrial EMD times were found to be lower in survived HD patients. With the cut-off median values of 3.5 g/dl for albumin, 0.87 mg/dl for CRP, 157 mg/dl for total cholesterol and 151 mg/dl for triglyceride, the Kaplan-Meier curves demonstrated significant differences in terms of all-cause mortality. We also demonstrated the Kaplan-Meier survival curves of HD patients according to tertile values of LIAT. Cox regression analysis revealed that increased CRP and higher LIAT were found to be independent predictors of combined CV events. Conclusions: Increased LIAT and inflammation were found to be closely associated with 2 years combined CV events and all-cause mortality in HD patients. (C) 2015 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000441099
dc.identifier.endpage249en_US
dc.identifier.issn0250-8095
dc.identifier.issn1421-9670
dc.identifier.issue3en_US
dc.identifier.pmid26484658en_US
dc.identifier.scopus2-s2.0-84945117746en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage239en_US
dc.identifier.urihttps://doi.org/10.1159/000441099
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14272
dc.identifier.volume42en_US
dc.identifier.wosWOS:000364611100008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofAmerican Journal Of Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLeft Intra-Atrial Electromechanical Delay Timeen_US
dc.subjectMalnutritionen_US
dc.subjectCombined Cv Eventsen_US
dc.subjectHemodialysisen_US
dc.titlePredictive Value of Atrial Electromechanical Delay on Long-Term Cardiovascular Outcomes in Hemodialysis Patientsen_US
dc.typeArticleen_US

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