Oncological outcomes for encapsulated papillary carcinoma of the breast: Multicentric study of Turkish Society for Radiation Oncology breast cancer study group (TROD 06-014 study)

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dc.contributor.authorGurdal, Necla
dc.contributor.authorYildirim, Berna Akkus
dc.contributor.authorGursel, Ozge Kandemir
dc.contributor.authorOzkurt, Selnur
dc.contributor.authorIbis, Kamuran
dc.contributor.authorGultekin, Melis
dc.contributor.authorTepetam, Huseyin
dc.date.accessioned2024-02-23T14:24:01Z
dc.date.available2024-02-23T14:24:01Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractBackgroundEncapsulated papillary carcinoma (EPC) is a rare malignant papillary breast cancer accounting for approximately .5%-2% of all breast tumors. The aim of this multicenter study was to evaluate clinicopathologic features of EPC in addition to oncological outcomes and radiotherapy (RT) details. MethodsFrom 10 different academic hospitals in Turkey, we obtained pathology reports of 80 patients with histologically confirmed EPC between 2005 and 2022. Demographic, diagnostic, and treatment data were collected from medical records, retrospectively. Local failure, distant progression, toxicity-adverse effects, overall survival (OS), and disease-free survival were evaluated, and survival analyzes were performed using the Kaplan-Meier method. ResultsEighty patients with the diagnosis of misspelled sorry (ECP) were retrospectively evaluated. The median age of the patients was 63 (range, 35-85). After a median follow-up of 48 (range; 6-206) months, local recurrence was observed in three patients (4%). Local recurrence was less common in the patients who received whole breast RT with a tumour bed boost (p = .025). There were not any distant metastasis or disease-related death. RT was applied to 61% of the cases, and no treatment-related grade 3 or higher toxicity was reported in any of the patients. Five year OS, cancer-specific survival (CSS), and were observed as 85%, 100%, and 96%, respectively. ConclusionsECP is a rare, slow-progressing breast carcinoma associated with good prognosis, it is a disease of elderly patient, and usually occurs in postmenopausal women. It responds extremely well to optimal local treatments and appropriate adjuvant treatments on a patient basis, and has excellent OS and CSS ratios.en_US
dc.identifier.doi10.1111/ajco.13893
dc.identifier.endpageE282en_US
dc.identifier.issn1743-7555
dc.identifier.issn1743-7563
dc.identifier.issue5en_US
dc.identifier.pmid36464924en_US
dc.identifier.scopus2-s2.0-85143991946en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpageE273en_US
dc.identifier.urihttps://doi.org/10.1111/ajco.13893
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13773
dc.identifier.volume19en_US
dc.identifier.wosWOS:000895924000001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAsia-Pacific Journal Of Clinical Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBreast Canceren_US
dc.subjectEncapsulated Papillary Carcinomaen_US
dc.subjectIntracystic Papillary Carcinomaen_US
dc.subjectPapillary Neoplasmsen_US
dc.subjectRadiotherapyen_US
dc.titleOncological outcomes for encapsulated papillary carcinoma of the breast: Multicentric study of Turkish Society for Radiation Oncology breast cancer study group (TROD 06-014 study)en_US
dc.typeArticleen_US

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