Assessment of the left atrial volume index and plasma NT-proANP level in patients with acute ST-elevation myocardial infarction

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dc.contributor.authorBacaksiz, Ahmet
dc.contributor.authorVatankulu, Mehmet Akif
dc.contributor.authorKayrak, Mehmet
dc.contributor.authorTelli, Hasan Huseyin
dc.contributor.authorAyhan, Selim S.
dc.contributor.authorSonmez, Osman
dc.contributor.authorAlp, Ayse
dc.date.accessioned2024-02-23T14:44:48Z
dc.date.available2024-02-23T14:44:48Z
dc.date.issued2013
dc.departmentNEÜen_US
dc.description.abstractOBJECTIVES: Acute ST-elevation myocardial infarction is associated with ventricular dysfunction due to ischemia-induced progressive myocardial damage. The decrease in ventricular compliance causes left atrial dilatation and stretching of the atrial myocardium, which are the main stimuli for the secretion of atrial natriuretic peptide. The aim of this study was to evaluate left atrial dimensions and atrial natriuretic peptide levels in patients early after their first acute ST-elevation myocardial infarction and assess the probable interaction between coronary lesions and these measurements. METHODS: A total of 110 patients with acute myocardial infarction and 50 controls were studied. Plasma atrial natriuretic peptide was measured at admission. Left ventricular function, diameter, and volume index were evaluated using transthoracic echocardiography. Gensini and vessel scores of the patients who underwent coronary angiography were calculated. RESULTS: Plasma atrial natriuretic peptide in the patients with myocardial infarction was increased compared with that in controls (3.90 +/- 3.75 vs. 1.35 +/- 0.72 nmol/L, p<0.001). Although the left atrial diameter was comparable in patients and controls, the left atrial volume index was increased in patients with acute myocardial infarction (26.5 +/- 7.1 vs. 21.3 +/- 4.9 mL/m(2), p<0.01). Multivariate regression analysis showed a strong independent correlation between the left atrial volume index and the plasma atrial natriuretic peptide level (beta = 0.23, p = 0.03). CONCLUSIONS: The left atrial volume index and plasma atrial natriuretic peptide level were correlated in patients with acute myocardial infarction.en_US
dc.identifier.doi10.6061/clinics/2013(07)18
dc.identifier.endpage1003en_US
dc.identifier.issn1807-5932
dc.identifier.issue7en_US
dc.identifier.pmid23917666en_US
dc.identifier.scopus2-s2.0-84881054072en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage997en_US
dc.identifier.urihttps://doi.org/10.6061/clinics/2013(07)18
dc.identifier.urihttps://hdl.handle.net/20.500.12452/17122
dc.identifier.volume68en_US
dc.identifier.wosWOS:000322601600018en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHospital Clinicas, Univ Sao Pauloen_US
dc.relation.ispartofClinicsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMyocardial Infarctionen_US
dc.subjectAtrial Natriuretic Peptideen_US
dc.subjectHeart Atriaen_US
dc.titleAssessment of the left atrial volume index and plasma NT-proANP level in patients with acute ST-elevation myocardial infarctionen_US
dc.typeArticleen_US

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