Decreased coronary blood flow velocity in patients with aortic insufficiency but normal coronary arteries: the use of TIMI frame count in aortic insufficiency cases

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dc.contributor.authorIcli, Abdullah
dc.contributor.authorMutlu, Halil
dc.contributor.authorKarabag, Turgut
dc.contributor.authorKahraman, Halil
dc.date.accessioned2024-02-23T14:48:43Z
dc.date.available2024-02-23T14:48:43Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractPatients with aortic insufficiency (Al) may suffer from anginapector is in the absence of obstructive coronaryartery disease. In this study, we aimed to investigate coronary blood flow using the thrombolysis in myocardial infarction (TIMI) frame count (TFC) method in patients with Al and normal coronaryarteries. The study included 64 patients (Group 1; meanage 62.4 +/- 13.2 years) with moderate to severe Al who had under gonecoronaryangio graphy that resulted in angiographically normal coronaries, and 42 patients with a typical chest pain and angiographically normal coronaryarteriogram (Group 2; meanage 58.8 +/- 9.8 years). All patients under went coronaryangiography either to exclude coronaryartery disease or to evaluate their coronaryanatomy before aorticvalve replacement. TFC was calculated and compared for each artery, including the left anterior descending (LAD), circumflex (LCX), and right coronaryartery (RCA) in both groups. The base line characteristics of the study groups were similar. In both groups, TIMI-3 flow was present in eachartery at the time of arteriography, and the coronaryarteries were entirely normal. LCx and RCA frame counts and corrected LAD frame counts were significantly higher in Group 1 than in Group 2 (26.4 +/- 2.1 vs. 24.3 +/- 3.6, P < 0.05; 22.1 +/- 2.3 vs. 20.5 +/- 2.9, P <0.05; and 22.5 +/- 1.8 vs. 20.5 +/- 2.4, P <0.05, respectively). The TFC method may be used as a marker forcoronaryflowvelocity in patients with aortic insuffiency and angiographically normal coronaryarteries toestimate decreased coronary blood flow velocity.en_US
dc.identifier.endpage16363en_US
dc.identifier.issn1940-5901
dc.identifier.issue9en_US
dc.identifier.pmid26629157en_US
dc.identifier.scopus2-s2.0-84946593867en_US
dc.identifier.startpage16358en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12452/17800
dc.identifier.volume8en_US
dc.identifier.wosWOS:000365273300096en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherE-Century Publishing Corpen_US
dc.relation.ispartofInternational Journal Of Clinical And Experimental Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectThrombolysis In Myocardial Infarction Framecounten_US
dc.subjectAorticin Sufficiencyen_US
dc.subjectCoronary Blood Flow Velocityen_US
dc.titleDecreased coronary blood flow velocity in patients with aortic insufficiency but normal coronary arteries: the use of TIMI frame count in aortic insufficiency casesen_US
dc.typeArticleen_US

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