Evaluation of coagulation with TEG in patients diagnosed COVID-19

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dc.contributor.authorVatansev, Hulya
dc.contributor.authorKaraselek, Mehmet Ali
dc.contributor.authorYilmaz, Resul
dc.contributor.authorKuccukturk, Serkan
dc.contributor.authorTopal, Ahmet
dc.contributor.authorYosunkaya, Sebnem
dc.contributor.authorKucuk, Adem
dc.date.accessioned2024-02-23T14:37:25Z
dc.date.available2024-02-23T14:37:25Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractBackground and aim: A high D-dimer level may indicate the risk of coagulopathy and mortality in COVID-19 patients. Thromboelastography (TEG) is a test that evaluates clot formation and fibrinolysis in real-time, unlike routine coagulation tests. The study aimed to investigate the coagulation process with TEG in patients diagnosed with COVID-19. Materials and Methods: The study was performed at our university hospital, chest diseases outpatient clinic as a cross-section study. A total of 51 patients with 23 high D-dimer levels group (HDG) and 28 low D-dimers group (LDG) were included in the study. TEG analysis was performed at the pretreatment evaluation in these two groups. Results: D-dimer and fibrinogen levels of the HDG were higher than those of the LDG (550 vs. 90 ng/mL, p < 0.001; 521 vs. 269 mg/ dL, p < 0.001, respectively). In TEG analysis, HDG's R and K values were lower than LDG, and HDG's Angle, MA, and CI values were higher than LDG (p = 0.037; p < 0.001; p < 0.001; p < 0.001; p < 0.001, respectively). ROC curve analysis suggested that the optimum TEG parameters cut-off points for thrombosis risk were as below: for K was <_2.1 min, for R was <_6.1 min, for Angle was >62 degrees, MA was 60.4 mm. Conclusion: Our study showed that the risk of thrombosis might increase in COVID-19 patients who are not hospitalized in the intensive care unit. Thrombosis risk should be investigated with TEG analysis and laboratory tests in every patient diagnosed with COVID-19, and treatment should be started for risky patients.en_US
dc.description.sponsorshipNecmettin Erbakan University Scientific Research Projects Coordination Unit [201218021]en_US
dc.description.sponsorshipWe would like to thank Necmettin Erbakan University Scientific Research Projects Coordination Unit for financially supporting this study (Project number: 201218021. There is no conflict of interest declared by the authors.en_US
dc.identifier.doi10.3906/sag-2106-379
dc.identifier.endpage38en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue1en_US
dc.identifier.pmid34773688en_US
dc.identifier.scopus2-s2.0-85125354001en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage32en_US
dc.identifier.urihttps://doi.org/10.3906/sag-2106-379
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16100
dc.identifier.volume52en_US
dc.identifier.wosWOS:000761923700004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectThromboelastographyen_US
dc.subjectCovid-19en_US
dc.subjectD-Dimeren_US
dc.subjectCoagulopathyen_US
dc.subjectThrombosisen_US
dc.titleEvaluation of coagulation with TEG in patients diagnosed COVID-19en_US
dc.typeArticleen_US

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