Effect of Vitamin D Deficiency on Hypertrophic Scarring

Basit Öğe Kaydı
dc.contributor.authorInce, Bilsev
dc.contributor.authorUyar, Ilker
dc.contributor.authorDadaci, Mehmet
dc.date.accessioned2024-02-23T14:21:09Z
dc.date.available2024-02-23T14:21:09Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractBACKGROUND Although many different diseases have been reported with vitamin D deficiency, the authors failed to find any studies on the association of hypertrophic scarring (HS) in the literature. OBJECTIVE The authors aimed to determine the relationship between vitamin D deficiency and HS and investigate the effect of replacement therapy on HS development in patients with vitamin D deficiency. PATIENTS AND METHODS Patients who presented to the authors' outpatient clinic with HS between 2013 and 2016 were included in the study. In the first stage, all the patients with HS complaints were assessed for vitamin D levels. In the second stage, 50 patients with a vitamin D level less than 25 ng/mL and a linear scar after at least 1 year of trauma were randomly divided into 3 groups. Group 1: patients who did not accept any medical or surgical treatment; Group 2: patients who were subjected to vitamin D replacement only; Group 3: patients who underwent surgical excision and suturation after vitamin D replacement. RESULTS A statistically significant correlation was found between HS and vitamin D levels (p < .05). A statistically significant decrease in scar width was observed in Group 3 (p < .05). CONCLUSION Increasing vitamin D levels to above 25 ng/mL before scar revision and vitamin D deficiency in patients with HS may help reduce scar width.en_US
dc.identifier.doi10.1097/DSS.0000000000001680
dc.identifier.endpage279en_US
dc.identifier.issn1076-0512
dc.identifier.issn1524-4725
dc.identifier.issue2en_US
dc.identifier.pmid30204734en_US
dc.identifier.scopus2-s2.0-85061117747en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage274en_US
dc.identifier.urihttps://doi.org/10.1097/DSS.0000000000001680
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13449
dc.identifier.volume45en_US
dc.identifier.wosWOS:000462415500014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofDermatologic Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titleEffect of Vitamin D Deficiency on Hypertrophic Scarringen_US
dc.typeArticleen_US

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