The Effects of Sleep Deprivation on Dissociation and Profiles of Mood, and Its Association with Biochemical Changes

dc.contributor.authorSelvi, Yavuz
dc.contributor.authorKilic, Sultan
dc.contributor.authorAydin, Adem
dc.contributor.authorOzdemir, Pinar Guzel
dc.date.accessioned2024-02-23T14:41:15Z
dc.date.available2024-02-23T14:41:15Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractIntroduction: Sleep deprivation is a method, which has being used in order to comprehend the functions of sleep both in healthy individuals and for the patients of depression with in treatment, for a long time. The objective of our present study is to examine the relation between hormonal values, which are known for being related to the effects of these said changes determined in the mood, dissociation and thought suppression in healthy individuals after one night of sleep deprivation implementation. Methods: One night sleep deprivation was performed on a total of thirty-two healthy volunteers (16 males and 16 females) who were included in the study. Blood samples were taken from the individuals before and after sleep deprivation implementation in order to determine cortisol, dehydroepiandrosterone-sulfate (DHEA-S) and Thyroid Functions' Levels tests. In order to evaluate the effects of the sleep deprivation on moods, White Bear Suppression Inventory (WBSI) has been conducted, with an aim of evaluating thought suppression, Profile of Mood States (POMS), Dissociative Experiences Scale (DES) with a purpose of realizing any dissociation tendency. Results: On the individuals who have been implemented for sleep deprivation, a decrease on depression and vigor-activity sub-scales values was detected, and an increase was determined on fatigue sub-scales values of POMS. While the values of DES were found to have been statistically increased after sleep deprivation, also a significant decrease was determined on WBSI values. Even if there hasn't been any significant statistical change determined on cortisol levels after sleep deprivation, yet there had been some significant changes detected on Thyroid Stimulating Hormone (TSH), fT3, fT4, and DHEA-S levels. Decrease in POMS depression sub-scale values and increase on fatigue sub-scale values were determined on the individuals whose sT4 levels were found to be increased significantly in statistic manner after the sleep deprivation. Conclusion: According to the results of our study, sleep deprivation for one night was determined to cause decrease on depressive mood, increase on dissociative symptoms and to lower the tendency of suppressing the unwanted thoughts, consciously. The fact of being obtained lower depression values, on the individuals with the increased DHEA-S levels after the sleep deprivation meets with the information claiming that the high DHEA-S levels may be deemed as protectors against the negative effects of the stress.en_US
dc.description.sponsorshipYuzuncu Yil University Scientific Research Project [2010 TF U143]en_US
dc.description.sponsorshipThe authors declared that this study has received financial support from Yuzuncu Yil University Scientific Research Project (Project No: 2010 TF U143).en_US
dc.identifier.doi10.5152/npa.2015.7116
dc.identifier.endpage88en_US
dc.identifier.issn1300-0667
dc.identifier.issue1en_US
dc.identifier.pmid28360682en_US
dc.identifier.scopus2-s2.0-84926658431en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage83en_US
dc.identifier.urihttps://doi.org/10.5152/npa.2015.7116
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16749
dc.identifier.volume52en_US
dc.identifier.wosWOS:000351851100017en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofNoropsikiyatri Arsivi-Archives Of Neuropsychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSleep Deprivationen_US
dc.subjectDissociationen_US
dc.subjectMooden_US
dc.subjectBiochemical Changesen_US
dc.titleThe Effects of Sleep Deprivation on Dissociation and Profiles of Mood, and Its Association with Biochemical Changesen_US
dc.typeArticleen_US

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