Assessment of Ocular Surface in Patients With Ankylosing Spondylitis

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dc.contributor.authorOltulu, Refik
dc.contributor.authorTurk, Huseyin Bugra
dc.contributor.authorOltulu, Pembe
dc.contributor.authorTurk, Nazli
dc.contributor.authorSatirtav, Gunhal
dc.contributor.authorGunduz, Mehmet Kemal
dc.date.accessioned2024-02-23T14:21:10Z
dc.date.available2024-02-23T14:21:10Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractPurpose: To evaluate the clinical findings and ocular surface changes in patients with ankylosing spondylitis (AS). Methods: This prospective study involved 45 patients with AS (group 1) and 28 healthy subjects (group 2). Patients in group 1 were in the inactive period. The study subjects underwent a complete ophthalmic examination. The right eyes of the subjects in each group were tested for the study including slit-lamp examination, Schirmer I test, tear break-up time (TBUT), conjunctival impression cytology (CIC), and ocular surface disease index (OSDI). Results between the two groups were compared. Results: The mean Schirmer I test result was found as 12.2 +/- 8 mm in group 1 and 20.3 +/- 9.9 mm in group 2 (P<0.001), whereas the mean TBUT value was found as 3.8 +/- 1.9 sec in group 1 and 10.1 +/- 4.8 sec in group 2 (P<0.001). The OSDI scores were significantly higher in group 1 (36.5 +/- 19.4) than in group 2 (9.1 +/- 12.9, P<0.001). The CIC scores were significantly higher in group 1 (2.12 +/- 0.7) than in group 2 (0.57 +/- 0.6, P<0.001). Notably, none of the patients in group 1 showed grade 0 differentiation, and none of the patients in group 2 showed grade 2 or 3 differentiation. The CIC scores were significantly higher in group 1 (2.12 +/- 0.7) than in group 2 (0.57 +/- 0.6, P<0.001). Conclusion: Ocular surface changes, including squamous metaplasia in the bulbar conjunctiva, can be observed in patients with AS.en_US
dc.identifier.doi10.1097/ICL.0000000000000592
dc.identifier.endpage34en_US
dc.identifier.issn1542-2321
dc.identifier.issn1542-233X
dc.identifier.issue1en_US
dc.identifier.pmid30817331en_US
dc.identifier.scopus2-s2.0-85076394905en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage31en_US
dc.identifier.urihttps://doi.org/10.1097/ICL.0000000000000592
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13461
dc.identifier.volume46en_US
dc.identifier.wosWOS:000525314700006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofEye & Contact Lens-Science And Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnkylosing Spondylitisen_US
dc.subjectDry Eyeen_US
dc.subjectConjunctival Impression Cytologyen_US
dc.subjectOsdien_US
dc.subjectRheumatic Diseaseen_US
dc.titleAssessment of Ocular Surface in Patients With Ankylosing Spondylitisen_US
dc.typeArticleen_US

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