Electrocardiographic Alterations in Patients with Common Variable Immune Deficiency

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dc.contributor.authorAlsancak, Yakup
dc.contributor.authorColkesen, Fatih
dc.date.accessioned2024-02-23T14:38:08Z
dc.date.available2024-02-23T14:38:08Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractIntroduction: Common variable immunodeficiency (CVID) is the most heterogeneous group among the antibody deficiency syndromes, but its effects on the cardiovascular system have not yet been clearly identified. Here, we aimed to investigate the arrhythmogenic effects of this disease with electrocardiography. Methods: The study included 30 CVID patients and 30 control subjects matched for age and comorbidities. Electrocardiographic and echocardiographic values of all participants were recorded. QRS, QT, Tp-e were measured manually. QTc was calculated using Bazett's formula. Then, Tp-e/QT, Tp-e/QTc, QT/QRS, and QTc/QRS ratios were calculated and compared between the groups. Results: PR interval and P-wave dispersion were found to be higher in the CVID group. In addition, the QT interval and corrected QT interval, T peak-to-end interval were higher in the CVID arm, and the index of cardiac electrophysiological balance value obtained with the QT/QRS ratio was also higher in the CVID group. The number of patients with P terminal force was also higher in the CVID group. Conclusion: As a result of this study, it was found that CVID patients have a higher incidence of developing arrhythmia than normal healthy individuals.en_US
dc.identifier.doi10.4274/imj.galenos.2020.47855
dc.identifier.endpage114en_US
dc.identifier.issn2619-9793
dc.identifier.issn2148-094X
dc.identifier.issue2en_US
dc.identifier.startpage109en_US
dc.identifier.urihttps://doi.org/10.4274/imj.galenos.2020.47855
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16376
dc.identifier.volume21en_US
dc.identifier.wosWOS:000520493300006en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherIstanbul Training & Research Hospitalen_US
dc.relation.ispartofIstanbul Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectArrhythmiaen_US
dc.subjectCviden_US
dc.subjectElectrocardiographyen_US
dc.titleElectrocardiographic Alterations in Patients with Common Variable Immune Deficiencyen_US
dc.typeArticleen_US

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