Evaluation of the Sheffield score, clinical characteristics, and the therapeutic approach in children with upper gastrointestinal system bleeding

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dc.contributor.authorYucel, A.
dc.date.accessioned2024-02-23T14:49:37Z
dc.date.available2024-02-23T14:49:37Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractOBJECTIVE: Unlike adults, there is no valid and reliable scoring system for upper gastrointestinal system bleeding (UGB) in children. The Sheffield scoring system, which is awaiting confirmation, is the single scoring system which can be predictive for children who require high-risk, endoscopic therapeutic intervention. The aim of this study was to evaluate the efficacy of the Sheffield scoring system, the clinical characteristics of patients, and the treatments applied. PATIENTS AND METHODS: Evaluation was made of a total of 86 children with UGB who underwent esophagogastroduodenoscopy and for whom the Sheffield score was calculated. The decision for therapeutic intervention was made according to the clinical status independently of the score. The demographic data of the patients, clinical symptoms and findings, risk factors, and treatments were examined retrospectively. RESULTS: The Sheffield score was calculated as >8 in 67.4% of the patients and > 8 in 32.6%. Endoscopic hemostatic intervention was applied to 15.1% of the patients. The rate of therapeutic endoscopy was significantly high in the high-score group. In 11 patients with Sheffield score >8, the bleeding was brought under control with octreotide treatment administered before endoscopy and no invasive intervention was applied. The sensitivity and specificity of the Sheffield score were determined to be at a good level in the prediction of the requirement for therapeutic endoscopy and octreotide treatment. CONCLUSIONS: The Sheffield score can reliably predict the need for endoscopic treatment with high sensitivity and specificity. In children with a high score, the need for an invasive intervention can be reduced with the administration of vasoactive treatment before esophagogastroduodenoscopy. The Sheffield score can thus be of guidance in the determination of the need for vasoactive treatment.en_US
dc.identifier.endpage7995en_US
dc.identifier.issn1128-3602
dc.identifier.issue21en_US
dc.identifier.pmid36394749en_US
dc.identifier.scopus2-s2.0-85141956587en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage7986en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12452/18280
dc.identifier.volume26en_US
dc.identifier.wosWOS:000922026100030en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical And Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectUpper Gastrointestinal System Bleedingen_US
dc.subjectScoring Systemen_US
dc.subjectChildrenen_US
dc.subjectEsophagogastroduodenoscopyen_US
dc.subjectInvasive Endoscopic Interventionen_US
dc.subjectOctreotideen_US
dc.titleEvaluation of the Sheffield score, clinical characteristics, and the therapeutic approach in children with upper gastrointestinal system bleedingen_US
dc.typeArticleen_US

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