Assessment of abdominal aortic calcification at different stages of chronic kidney disease

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dc.contributor.authorBiyik, Zeynep
dc.contributor.authorSelcuk, Nedim Yilmaz
dc.contributor.authorTonbul, Halil Zeki
dc.contributor.authorAnil, Melih
dc.contributor.authorUyar, Mehmet
dc.date.accessioned2024-02-23T13:59:27Z
dc.date.available2024-02-23T13:59:27Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractVascular calcifications that may cause cardiovascular disease are highly prevalent in chronic kidney disease (CKD). In this study, we aimed to determine abdominal aorta calcifications (AAC) in predialysis and hemodialysis patients by lateral lumbar radiography and to investigate factors that were associated with the calcifications. Two hundred and fifty-nine adult chronic hemodialysis patients, 300 predialysis CKD patients and 60 healthy subjects with normal kidney function as a control group were enrolled in the study. Lateral lumbar radiography was used to measure AAC. Calcified deposits of the abdominal aorta wall at the level of the first through fourth lumbar vertebrae were graded by a 24-point scoring system. AAC prevalence (AAC score aeyen1) was significantly different in hemodialysis, predialysis and control groups (71.8, 45.7 and 33.3 %, respectively; p < 0.001). AAC prevalence in CKD stages 1, 2, 3, 4 and 5 predialysis patients was 26.6, 43.3, 40, 58.3 and 55 %, respectively. AAC scores of the hemodialysis group were higher than of the predialysis group (p < 0.001) and the control group (p < 0.001). AAC scores of the predialysis group were not higher than of the control group (p = 0.314). AAC scores of the hemodialysis group were significantly higher than of the control group (p < 0.001) and stage 1 (p < 0.001), stage 2 (p = 0.001) and stage 3 predialysis groups (p = 0.002). Age (p < 0.001), presence of diabetes mellitus (p < 0.001) and serum phosphorus levels (p = 0.011) were found to be independent predictors of calcification in the hemodialysis group. Age (p < 0.001), serum phosphorus levels (p = 0.007) and history of cardiovascular disease (p = 0.014) were found to be independent predictors of calcification in the predialysis group. Abdominal aortic calcification is highly prevalent in the hemodialysis population. Strict phosphorus control should be implemented to the predialysis and hemodialysis patients.en_US
dc.identifier.doi10.1007/s11255-016-1413-x
dc.identifier.endpage2068en_US
dc.identifier.issn0301-1623
dc.identifier.issn1573-2584
dc.identifier.issue12en_US
dc.identifier.pmid27620901en_US
dc.identifier.scopus2-s2.0-84987668176en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2061en_US
dc.identifier.urihttps://doi.org/10.1007/s11255-016-1413-x
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11202
dc.identifier.volume48en_US
dc.identifier.wosWOS:000387600200016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Urology And Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAbdominal Aortic Calcificationen_US
dc.subjectHemodialysisen_US
dc.subjectPredialysisen_US
dc.subjectVascular Calcificationen_US
dc.titleAssessment of abdominal aortic calcification at different stages of chronic kidney diseaseen_US
dc.typeArticleen_US

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