Paediatric systemic lupus erythematosus: A single referral centre experience

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dc.contributor.authorAtas, Bulent
dc.contributor.authorBulut, Mustafa
dc.contributor.authorSap, Fatih
dc.contributor.authorYazar, Abdullah
dc.contributor.authorAkin, Fatih
dc.contributor.authorPoyraz, Necdet
dc.contributor.authorTokgoz, Huseyin
dc.date.accessioned2024-02-23T14:41:32Z
dc.date.available2024-02-23T14:41:32Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractIn this study, the clinical and laboratory findings, management and follow-up of 32 children with paediatric systemic lupus erythematosus (pSLE) were evaluated to determine the prognostic factors in pSLE. Of the 32 patients, 25 (78.1%) were females. Age at onset of symptoms and diagnosis in the patients were 147.6 +/- 49 months and 154.3 +/- 48 months, respectively. The most common symptom on admission were joint problems, seen in 25 (78.1%) patients. Haematological alterations were seen in 25 (78.1%) cases during follow-up. Lupus nephritis was diagnosed in 10 (31.2%) patients. Malar rash was seen in a total of 12 (37.5%) patients during follow up, however it had been noted in five (15.6%) patients on admission. Antinuclear antibody and anti-dsDNA were positive in all patients and 31 (96.8%) patients, respectively. Decreased complement 3 and 4 levels were noted in 23 (71.8%) patients. Antiphospholipid antibody was studied in 27 patients and it was found to be positive in 13 (48.1%) patients. In conclusion, based on our findings, we would like to emphasize that pSLE has a large and remarkable clinical and laboratory findings.en_US
dc.identifier.doi10.5455/JPMA.61641
dc.identifier.endpage139en_US
dc.identifier.issn0030-9982
dc.identifier.issue1en_US
dc.identifier.pmid33484540en_US
dc.identifier.scopus2-s2.0-85100325903en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage136en_US
dc.identifier.urihttps://doi.org/10.5455/JPMA.61641
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16894
dc.identifier.volume71en_US
dc.identifier.wosWOS:000641903600019en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPakistan Medical Assocen_US
dc.relation.ispartofJournal Of The Pakistan Medical Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectComplementen_US
dc.subjectJoint Involvementen_US
dc.subjectPaediatric Systemic Lupus Erythematosusen_US
dc.titlePaediatric systemic lupus erythematosus: A single referral centre experienceen_US
dc.typeArticleen_US

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