Evaluation of Mandibular Morphometry in the Bisphosphonate Users

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dc.contributor.authorBusra, Tanrikol
dc.contributor.authorGuldane, Magat
dc.date.accessioned2024-02-23T14:37:40Z
dc.date.available2024-02-23T14:37:40Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractThis study aimed to evaluate the effects of bisphosphonates on the mandibular bone. Bisphosphonates are drugs which are commonly used in the treatment of many diseases related to bone metabolism such as osteoporosis, breast cancer capable of hone metastasis, prostate and lung cancer and bone cancer such as multiple myeloma. Our study group consisted of a total of 100 panoramic radiographs which were obtained from the examinations of 50 individuals using bisphosphonate and 50 individuals in the control group who applied for routine dental examination to the Department of Oral and Maxillofacial Radiology of Akdeniz University Dentistry Faculty between years 2015 and 2016.The calculations of the mandibular cortical thickness (MCT), mandibular cortical index (MCI), panoramic mandibular index (PMI), condylar angle (CA), gonial angle (GA), antegonial angle (AGA), antegonial depth (AGD) and antegonial index (AGI) were made for each patient. It was found that both left and the right MCT and only the left PMI were affected by age. Only the left AGA and both the left and right MCT and AGD were affected by gender. The left and right AGI measurements of the patients using bisphosphonates were statistically lower than those of the individuals in the control group. Our results suggested that bisphosphonates had various effects on the jaw bones. However, further comprehensive studies need to be made to evaluate the long-term effect of bisphosphonates on bone metabolism.en_US
dc.identifier.doi10.4067/S0717-95022019000200654
dc.identifier.endpage663en_US
dc.identifier.issn0717-9502
dc.identifier.issn0717-9367
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85066789437en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage654en_US
dc.identifier.urihttps://doi.org/10.4067/S0717-95022019000200654
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16191
dc.identifier.volume37en_US
dc.identifier.wosWOS:000466984400039en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSoc Chilena Anatomiaen_US
dc.relation.ispartofInternational Journal Of Morphologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBisphosphonatesen_US
dc.subjectMandibleen_US
dc.subjectPanoramic Radiographyen_US
dc.titleEvaluation of Mandibular Morphometry in the Bisphosphonate Usersen_US
dc.typeArticleen_US

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