Effects of mandatory salt iodization on breast milk, urinary iodine concentrations, and thyroid hormones: is iodine deficiency still a continuing problem?

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dc.contributor.authorOzberk, D. Isiklar
dc.contributor.authorKutlu, R.
dc.contributor.authorKilinc, I.
dc.contributor.authorKilicaslan, A. O.
dc.date.accessioned2024-02-23T14:00:11Z
dc.date.available2024-02-23T14:00:11Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractPurposeTo investigate whether mandatory use of iodized salt in Turkey, since 1999 has sufficient effects on pregnant women and their newborns' urinary iodine concentrations (UIC), maternal and newborns' thyroid function tests and breast milk iodine concentrations (BMIC).MethodsThis cross-sectional analytical-type study was conducted in an obstetrics and gynecology hospital in Konya, Turkey. One hundred and seven pregnant women and their 107 full-term newborns were included into the study. Levels of pregnant women and their newborns' UIC, thyroid-stimulated hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4), thyroglobulin (Tg), and BMIC were studied.ResultsOf 107 women with term pregnancy, mean TSH value and hypothyroidism frequency were found as 2.341.33 mIU/L and 18.7%, respectively. Cord blood TSH level was found higher (10 mIU/L) in five newborns. Accordingly, the incidence of transient congenital hypothyroidism was 4.7% (5/107). Tg levels were observed to be higher in 50.5% of newborns and 22.4% of pregnant women. Frequency of iodized salt use in pregnancies was detected as 96.3% in general population, 97.5% in urban, and 92.9% in rural areas. Of pregnancies and newborns, 57.9 and 53.3% were found to have deficient urinary iodine, respectively, and BMIC deficiency was detected as 52.0%. There was a significant positive correlation between pregnant women's UIC, and newborns' UIC and BMIC.Conclusions p id=Par4 Despite the effective struggle with iodine deficiency and salt iodination control program in Konya, we concluded that iodine deficiency still persists as a significant problem in pregnancies.en_US
dc.description.sponsorshipNecmettin Erbakan University Scientific Research Coordination Center (BAP)en_US
dc.description.sponsorshipWe wish to thank the Necmettin Erbakan University Scientific Research Coordination Center (BAP) for the financial support to this study. We also thank to the mothers and their infants for their participation in this study.en_US
dc.identifier.doi10.1007/s40618-018-0930-0
dc.identifier.endpage418en_US
dc.identifier.issn0391-4097
dc.identifier.issn1720-8386
dc.identifier.issue4en_US
dc.identifier.pmid30099723en_US
dc.identifier.scopus2-s2.0-85051499459en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage411en_US
dc.identifier.urihttps://doi.org/10.1007/s40618-018-0930-0
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11488
dc.identifier.volume42en_US
dc.identifier.wosWOS:000463248300006en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal Of Endocrinological Investigationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBreast Milk Iodine Concentrationen_US
dc.subjectUrinary Iodine Concentrationen_US
dc.subjectNewbornen_US
dc.subjectPregnanten_US
dc.subjectThyroid Hormonesen_US
dc.titleEffects of mandatory salt iodization on breast milk, urinary iodine concentrations, and thyroid hormones: is iodine deficiency still a continuing problem?en_US
dc.typeArticleen_US

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