Effect of Maternal Depression on Brain-derived Neurotrophic Factor Levels in Fetal Cord Blood

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dc.contributor.authorSonmez, Erdem Onder
dc.contributor.authorUguz, Faruk
dc.contributor.authorSahingoz, Mine
dc.contributor.authorSonmez, Gulsum
dc.contributor.authorKaya, Nazmiye
dc.contributor.authorCamkurt, Mehmet Akif
dc.contributor.authorGokmen, Zeynel
dc.date.accessioned2024-02-23T14:44:57Z
dc.date.available2024-02-23T14:44:57Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractObjective: We aimed to assess the association between cord blood brain-derived neurotrophic factor (BDNF) concentration and maternal depression during pregnancy. Methods: A total of 48 pregnant women, admitted for elective caesarean section to Department of Obstetrics and Gynecology, The Konya Research and Training Hospital and Konya Necmettin Erbakan University Meram Medical Faculty, were included in this study. The study group included 23 women diagnosed as having depression during pregnancy and the control group included 25 pregnant women who did not experience depression during pregnancy. Results: The groups had similar sociodemographic characteristics. Cord blood BDNF concentration was significantly lower in babies born to mothers with major depression as compared with those in the control group. We didn't find any correlation between the umbilical cord blood BDNF levels and BDI scores. Conclusion: The results suggest that the existence of major depression in pregnant women may negatively affect fetal circulating BDNF levels.en_US
dc.identifier.doi10.9758/cpn.2019.17.2.308
dc.identifier.endpage313en_US
dc.identifier.issn1738-1088
dc.identifier.issn2093-4327
dc.identifier.issue2en_US
dc.identifier.pmid30905131en_US
dc.identifier.scopus2-s2.0-85065224968en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage308en_US
dc.identifier.urihttps://doi.org/10.9758/cpn.2019.17.2.308
dc.identifier.urihttps://hdl.handle.net/20.500.12452/17167
dc.identifier.volume17en_US
dc.identifier.wosWOS:000461148900017en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKorean Coll Neuropsychopharmacologyen_US
dc.relation.ispartofClinical Psychopharmacology And Neuroscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBrain-Derived Neurotrophic Factoren_US
dc.subjectPregnancyen_US
dc.subjectDepressionen_US
dc.subjectFetal Cord Blooden_US
dc.subjectNeurodevelopmenten_US
dc.titleEffect of Maternal Depression on Brain-derived Neurotrophic Factor Levels in Fetal Cord Blooden_US
dc.typeArticleen_US

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