High Triglyceride-Glucose Index is Associated With Poor Prognosis in Patients With Acute Coronary Syndrome in Long-Term Follow-Up

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dc.contributor.authorKaradeniz, Fatma Ozpamuk
dc.contributor.authorSancaktepe, Emine Altuntas
dc.contributor.authorKaradeniz, Yusuf
dc.date.accessioned2024-02-23T14:26:48Z
dc.date.available2024-02-23T14:26:48Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractThe triglyceride-glucose (TyG) index is calculated from fasting triglycerides and fasting glucose levels and is an indicator of insulin resistance. The present study investigates whether the TyG index has a role in predicting clinical outcomes in cases of acute coronary syndrome (ACS). This retrospective study included 646 patients with ST-elevation myocardial infarction (STEMI) and 1048 patients with non-ST-elevation myocardial infarction (NSTEMI). The association between major adverse cardiac events (MACEs) that developed in-hospital and at 60 months of follow-up and TyG index values were compared. Patients were divided into 2 groups: TyG index values of >= 8.65 and <8.65. During the hospital stay and 60 months of follow-up, 303 MACEs occurred. In both the STEMI and NSTEMI groups, as the TyG index increased, an increase was observed in MACE rates. MACE rates were also found to be highest in the group with TyG index >= 8.65 (P < .001). TyG index, C-reactive protein, and age were independent predictors of MACEs in both the NSTEMI and STEMI groups. The present study found a significant association between higher TyG index values and increased risk of MACEs in ACS patients. The TyG index may prove useful to predict clinical outcomes in ACS patients.en_US
dc.identifier.doi10.1177/00033197221124763
dc.identifier.endpage148en_US
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue2en_US
dc.identifier.pmid36112779en_US
dc.identifier.scopus2-s2.0-85138279662en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage139en_US
dc.identifier.urihttps://doi.org/10.1177/00033197221124763
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14342
dc.identifier.volume74en_US
dc.identifier.wosWOS:000854797500001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofAngiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTriglyceride-Glucose Indexen_US
dc.subjectAcute Coronary Syndromeen_US
dc.subjectInsulin Resistanceen_US
dc.subjectMajor Adverse Cardiovascular Eventen_US
dc.titleHigh Triglyceride-Glucose Index is Associated With Poor Prognosis in Patients With Acute Coronary Syndrome in Long-Term Follow-Upen_US
dc.typeArticleen_US

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