The effect of hypertension and obesity on left ventricular geometry and cardiac functions in children and adolescents

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dc.contributor.authorAlp, Hayrullah
dc.contributor.authorKaraarslan, Sevim
dc.contributor.authorEklioglu, Beray S.
dc.contributor.authorAtabek, Mehmet E.
dc.contributor.authorBaysal, Tamer
dc.date.accessioned2024-02-23T14:21:09Z
dc.date.available2024-02-23T14:21:09Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractObjectives:Obesity and hypertension are associated with structural and functional cardiac change in children and adults. The aim of the study is to evaluate the effect of hypertension and obesity on left ventricular geometric patterns and cardiac functions assessed by conventional and Doppler echocardiography.Methods:Four hundred and thirty obese children, aged 6-17 years and 150 age and sex-matched healthy controls, were included in the study. Left ventricular geometry was classified as concentric hypertrophy, eccentric hypertrophy, concentric remodeling and normal geometry.Results:Concentric hypertrophy group had the worst subclinical systolic and diastolic cardiac functions among all left ventricular geometric patterns. BMI and total adipose tissue mass are the predictors of abnormal ventricular geometry. Apart from the increase in carotid intima-media and epicardial adipose tissue thicknesses in different left ventricular geometry patterns, they are not predictable for abnormal geometry.Conclusion:The variety of alterations in cardiac function and morphology that has been observed in obese adults, appears to start earlier in life. Obesity and hypertension were clearly associated with the left ventricular geometry. Also, subclinical systolic and load-depended diastolic dysfunctions can be detected in obese hypertensive children with concentric hypertrophy.en_US
dc.identifier.doi10.1097/HJH.0000000000000176
dc.identifier.endpage1292en_US
dc.identifier.issn0263-6352
dc.identifier.issn1473-5598
dc.identifier.issue6en_US
dc.identifier.pmid24717446en_US
dc.identifier.scopus2-s2.0-84900457796en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1283en_US
dc.identifier.urihttps://doi.org/10.1097/HJH.0000000000000176
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13455
dc.identifier.volume32en_US
dc.identifier.wosWOS:000335534300019en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal Of Hypertensionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiac Functionsen_US
dc.subjectChildrenen_US
dc.subjectEchocardiographyen_US
dc.subjectHypertensionen_US
dc.subjectLeft Ventricular Geometric Patternsen_US
dc.subjectObesityen_US
dc.subjectPredictorsen_US
dc.titleThe effect of hypertension and obesity on left ventricular geometry and cardiac functions in children and adolescentsen_US
dc.typeArticleen_US

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