Lactate and NEWS-L are fair predictors of mortality in critically ill geriatric emergency department patients

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dc.contributor.authorDundar, Zerrin Defne
dc.contributor.authorKocak, Sedat
dc.contributor.authorGirisgin, Abdullah Sadik
dc.date.accessioned2024-02-23T14:00:18Z
dc.date.available2024-02-23T14:00:18Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractIntroduction: In this study, we aimed to investigate the prognostic power of the first lactate level measured in the emergency department (ED), National Early Warning Score (NEWS), and NEWS-lactate (NEWS-L) on ED admission in critically ill geriatric patients. Methods: This retrospective observational study was conducted in the ED of a university hospital. Consecutive patients >= 65 years of age admitted to our ED between July 1, 2017, and December 31, 2017, and transferred to the intensive care unit after the ED follow-up period were included in the study. The predictive performances of lactate, NEWS, and NEWS-L in terms of in-hospital mortality were compared. Results: A total of 455 patients were included in the statistical analyses. The in-hospital mortality rate was 22.9%. The mean lactate, NEWS, and NEWS-L of non-survivors was significantly higher than those of survivors (2.9 +/- 2.2 vs. 1.9 +/- 1.5 mmol/L, 8.9 +/- 4.1 vs. 6.1 +/- 3.7, and 11.8 +/- 5.0 vs. 8.1 +/- 4.4, respectively, for all p < 0.001). The AUCs of the lactate, NEWS, and NEWS-L were respectively 0.654 (95% CI 0.594-0.713), 0.686 (95% CI 0.628-0.744), and 0.714 (95% CI 0.658-0.770) in predicting in-hospital mortality. Conclusions: According to the results of this study, we conclude that ED admission lactate level and NEWS are low-accuracy predictors of in-hospital mortality in critically ill geriatric patients. Although the combination of lactate level with physiological parameters increases the predictive performances of both parameters, NEWS-L is still not a powerful predictor to make definitive clinical decisions for critically ill geriatric ED patients. (C) 2019 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ajem.2019.02.006
dc.identifier.endpage221en_US
dc.identifier.issn0735-6757
dc.identifier.issn1532-8171
dc.identifier.issue2en_US
dc.identifier.pmid30770240en_US
dc.identifier.scopus2-s2.0-85061300641en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage217en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajem.2019.02.006
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11548
dc.identifier.volume38en_US
dc.identifier.wosWOS:000535813900010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofAmerican Journal Of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLactateen_US
dc.subjectNewsen_US
dc.subjectNews-Lactateen_US
dc.subjectGeriatricsen_US
dc.subjectCritically Illen_US
dc.titleLactate and NEWS-L are fair predictors of mortality in critically ill geriatric emergency department patientsen_US
dc.typeArticleen_US

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