An Electrochemical Acetylcholinesterase Biosensor Based on Fluorene(bisthiophene) Comprising Polymer for Paraoxon Detection

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dc.contributor.authorCelik, Huzeyfe
dc.contributor.authorSoylemez, Saniye
dc.date.accessioned2024-02-23T12:06:43Z
dc.date.available2024-02-23T12:06:43Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractIn this study, a novel conductive polymer comprising biosensor based on poly-2,2 '-(9,9-dioctyl-9 h-fluorene-2,7-diyl)bistiophene (Poly(BT)) and acetylcholinesterase (AChE) was reported for the determination of paraoxon. This practical biosensor allowed to catalyze electrochemical oxidation of acetylthiocholine (+0.6 V vs. Ag reference). The detection range for acetylcholine chloride (AThCl) with Poly(BT)/AChE was found to be 0.025-4 mM. In pesticide analysis, wide linear ranges from 0.5 to 1 mu g/L and 1 to 14 mu g/L, and a low detection limit of 0.033 mu g/L were estimated. Under optimum operating conditions, the developed biosensor was used for pesticide detection in milk and tap water samples, effectively.en_US
dc.description.sponsorshipOrdu University BAP project [B-2111]en_US
dc.description.sponsorshipThe authors acknowledge support from Ordu University BAP project (Project No. B-2111).en_US
dc.identifier.doi10.1002/elan.202200271
dc.identifier.issn1040-0397
dc.identifier.issn1521-4109
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85137348329en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1002/elan.202200271
dc.identifier.urihttps://hdl.handle.net/20.500.12452/10558
dc.identifier.volume35en_US
dc.identifier.wosWOS:000849808200001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofElectroanalysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectElectrochemical Biosensoren_US
dc.subjectConjugated Polymeren_US
dc.subjectAcetylcholinesteraseen_US
dc.subjectEnzyme Immobilizationen_US
dc.subjectOrganophosphorus Pesticidesen_US
dc.titleAn Electrochemical Acetylcholinesterase Biosensor Based on Fluorene(bisthiophene) Comprising Polymer for Paraoxon Detectionen_US
dc.typeArticleen_US

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